A computational scheme connecting gene regulatory network dynamics with heterogeneous stem cell regeneration [PDF]
arXivStem cell regeneration is a vital biological process in self-renewing tissues, governing development and tissue homeostasis. Gene regulatory network dynamics are pivotal in controlling stem cell regeneration and cell type transitions. However, integrating the quantitative dynamics of gene regulatory networks at the single-cell level with stem cell ...
arxiv
Statistical and mathematical modeling of spatiotemporal dynamics of stem cells [PDF]
arXiv, 2018 Statistical and mathematical modeling are crucial to describe, interpret, compare and predict the behavior of complex biological systems including the organization of hematopoietic stem and progenitor cells in the bone marrow environment. The current prominence of high-resolution and live-cell imaging data provides an unprecedented opportunity to study
arxiv
A study of malignant lymphomas and leukemias.III. Stem cell, blast cell, and monocytic leukemias (with reference to their lymphogenous or myelogenous origin) [PDF]
, 1961 Gil M. Goldberg +2 more
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Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
Statistical interpretations and new findings on Variation in Cancer Risk Among Tissues [PDF]
arXiv, 2015 Tomasetti and Vogelstein (2015a) find that the incidence of a set of cancer types is correlated with the total number of normal stem cell divisions. Here, we separate the effects of standing stem cell number (i.e., organ or tissue size) and per stem cell lifetime replication rate. We show that each has a statistically significant and independent effect
arxiv
Erythropoietin in Vitro. II. Effect on "Stem Cells" [PDF]
, 1964 Allan J. Erslev
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Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Evaluation of a New Vasculature by High Resolution Light Microscopy: Primo Vessel and Node [PDF]
arXiv, 2016 The primo vascular system is composed of nodes and vessels. The bundle of sub-vessels of the promo vessel is laid into an external jacket composed of endothelial cells. The node is heterogeneous in nature, composed of twisted sub-vessel bundles that fill up nearly the entire node volume.
arxiv
Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging. [PDF]
, 1978 David Harrison +2 more
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Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi, 2019 A stem cell is an undifferentiated cell that can self-renew itself and can commit to a specific cell type. Depending on their residency, stem cells are classified into two main categories as embryonic stem cells and adult stem cells. According to their differentiation and developmental potential, stem cells may be classified as totipotent, pluripotent,
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