Results 181 to 190 of about 12,666,103 (318)

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

P1371: COMPARISON OF DIFFERENT METHODS FOR GENETIC CORRECTION OF GRISCELLI SYNDROME TYPE II-DERIVED STEM CELLS

HemaSphere, 2023
Özgür Dogus Erol, Burcu Pervin, Mehmet Emin Şeker, Burcu Özçimen, Şimal Şenocak, Sema Nur Gür, Hasan Basri Kiliç, Merve Gizer, Petek Korkusuz, Nico Peter van Til, Yusuf Çetin Kocaefe, Fatima Aerts Kaya   +11 more
doaj   +1 more source

Mechanisms and applications of mesenchymal stem cell exosomes in enhancing fertility. [PDF]

Stem Cell Res Ther
Wang Y, Wang R, Zhao Y, Han N, Han X, Shi T, Liu Y, Zhao N, Li S, Wang S, Li N, Zhu Y.   +11 more
europepmc   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Stem cell and gene therapies for leukodystrophies. [PDF]

Mol Ther Methods Clin Dev
Lin W, Zhang M, Zheng S, Lian Q.
europepmc   +1 more source

The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?

Cell Stem Cell, 2015
V. Plaks, Niwen Kong, Z. Werb
semanticscholar   +1 more source

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

Stem Cell-Derived Extracellular Vesicle Therapy in Ischemic Brain Injuries. [PDF]

J Stroke
Qiu C, Lindley A, Jia X.
europepmc   +1 more source

CD34⁺ acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax

, 2019
Katharina Mattes, Mylène Gerritsen, Hendrik Folkerts, Marjan Geugien, Fiona A. van den Heuvel, Arthur Flohr Svendsen, Guoqiang Yi, Joost H.A. Martens, Edo Vellenga   +8 more
openalex   +2 more sources

Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures

Nature Cell Biology, 2018
B. Sozen, G. Amadei, A. Cox, Ran Wang, Ellen Na, S. Czukiewska, L. Chappell, T. Voet, Geert Michel, N. Jing, D. Glover, M. Zernicka-Goetz   +11 more
semanticscholar   +1 more source