Results 271 to 280 of about 2,387,298 (366)

Generation of Advanced Blood–Brain Barrier Spheroids Using Human‐Induced Pluripotent Stem Cell‐Derived Brain Capillary Endothelial‐Like Cells

Advanced Biology, EarlyView.
In this article, the establishment and characterization of a self‐assembled 3D BBB spheroid model using human induced pluripotent stem cell (hiPSC)‐derived and primary cells is reported. Spheroids demonstrate in‐vivo like tight junction ultrastructure and, in comparison to 2D mono‐cultures, higher transcript expression of BBB specific genes.
Sanjana Mathew‐Schmitt, Sabrina Oerter, Evelin Reitenbach, Sabine Gätzner, Alevtina Höchner, Heinz‐Georg Jahnke, Jörg Piontek, Winfried Neuhaus, Andreas Brachner, Marco Metzger, Antje Appelt‐Menzel   +10 more
wiley   +1 more source

Polyomaviruses After Allogeneic Hematopoietic Stem Cell Transplantation. [PDF]

Viruses
Mendoza MA, Imlay H.
europepmc   +1 more source

The Stem Cell Niche: Interactions between Stem Cells and Their Environment [PDF]

Stem Cells International, 2018
Sari Pennings, Karen J. Liu, Hong Qian
openaire   +7 more sources

Considering the Risks and Costs of Solid Organ Xenotransplantation

Advanced Biology, EarlyView.
This perspective discusses the rationale, risks, and costs of whole‐organ xenotransplantation. It considers alternative strategies to obviate the demand for transplants and optimize allotransplantation systems and practices that do not impose xenotransplantation's harms and risks, and whether they are the most ethical and effective means to increase ...
Catharine E. Krebs, Janine McCarthy, Kristie Sullivan, James Craner, Brendan Parent, Ann Lam   +5 more
wiley   +1 more source

Isolation of murine pluripotent hemopoietic stem cells. [PDF]

, 1984
Jan Visser, J. G. J. Bauman, A Mulder, James F. Eliason, A.M. de Leeuw   +4 more
openalex   +1 more source

Preventive Effect of Metformin in Radiation‐Induced Xerostomia

Advanced Biology, EarlyView.
Head and neck cancer patients who received radiotherapy complain of severe dry mouth due to damage to the salivary glands. Metformin is an antidiabetic drug, but its radio‐protective effect has been reported. It is confirmed that metformin protects the salivary glands from radiation and provides evidence for the use of metformin in cancer treatment in ...
Sungryeal Kim, Jeong‐Mi Kim, Eun‐Jeong Jeon, Seo‐Young Park, Jin‐Mi Park, Jeong‐Seok Choi   +5 more
wiley   +1 more source

Diagnostic approach to limbal stem cell deficiency. [PDF]

Front Ophthalmol (Lausanne)
Lent-Schochet D, Akbar M, Hou JH, Farooq AV.   +3 more
europepmc   +1 more source

Depletion of TP53 in Human Pluripotent Stem Cells Triggers Malignant‐Like Behavior

Advanced Biology, EarlyView.
Human pluripotent stem cells (hPSCs) with TP53‐depleting mutations are generated, mimicking commonly occurring events in vitro. Loss of TP53 does not alter pluripotency status or in vitro differentiation potential but causes genetic instability and transcriptome changes and confers superior clonal and anchorage‐free growth and higher chemotherapeutic ...
Joaquin Montilla‐Rojo, Thomas F. Eleveld, Marnix van Soest, Sanne Hillenius, Dennis M. Timmerman, Ad J. M. Gillis, Bernard A. J. Roelen, Christine L. Mummery, Leendert H. J. Looijenga, Daniela C. F. Salvatori   +9 more
wiley   +1 more source

Editorial: Perivascular niche and stem cell signaling in tooth. [PDF]

Front Cell Dev Biol
Ouchi T, Shimizu E, Li B.
europepmc   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source