Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.
Cell, 2004 F. Arai +8 more
semanticscholar +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Micro- and nanoplastics influences in Parkinson's disease: lessons from human stem cell models. [PDF]
Front ToxicolMuhammad KN, Woodlief T, Wu X.
europepmc +1 more source
Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells.
Cell, 2015 Allon M. Klein +8 more
semanticscholar +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Cytomegalovirus reactivation and the prevalence in autologous hematopoietic stem cell transplantation. [PDF]
World J VirolMittal A, Hutchinson HJ, Lucke-Wold BP.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Analytical Performance of Two Flow Cytometry Systems for CD34⁺ Hematopoietic Stem Cell and CD3⁺ T-Cell Enumeration in Stem Cell Transplantation. [PDF]
CureusAziz H, Abdul Aziz S.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Mesangial hyaline degeneration after hematopoietic stem cell transplantation. [PDF]
Kidney Res Clin PractKawaguchi T, Yamaguchi Y.
europepmc +1 more source