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Marking stem cells

Nature Reviews Cancer, 2012
A paper in Cell identifies a subpopulation of intestinal stem cells that are characterized by the expression of LRIG1, which the authors show is a tumour suppressor.
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Stem cell factor

Journal of Leukocyte Biology, 1995
Abstract Stem cell factor (SCF) is the ligand for the tyrosine kinase receptor okit, which is expressed on both primitive and mature hematopoietic progenitor cells. In vitro, SCF synergizes with other growth factors, such as granulocyte colony-stimulating factor (G–CSF), granulocyte macrophage–colony-stimulating factor, and interleukin-3
Sidney Vaughn Suggs   +3 more
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Epigenetic Signatures In Stem Cells And Cancer Stem Cells

Epigenomics, 2009
The physiological properties of pluripotency in stem cells and the processes of cell specialization are governed by epigenetic mechanisms, as they are inheritable but not dependent on the cell genotype. There is cumulating evidence demonstrating the presence of cells with stem cell properties within tumors, suggesting that these cells are responsible ...
Hernandez-Vargas, Hector   +3 more
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Intestinal stem cell reserves

Nature Reviews Molecular Cell Biology, 2013
Intestinal quiescent cells are committed to differentiate into secretory cells but can be called into stem cell action after injury.
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Stem Cells and Cancer Stem Cells

2015
Nowadays, the definition “cancer stem cells” (CSCs) is widely accepted in the science community. Although, some authors think that this is a new definition in biology, the idea of CSCs has existed for more than 50 years. In recent years, the relations between “stem cells” and “cancer stem cells” gradually explored.
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Mesenchymal Stem Cells

Journal of Orthopaedic Research, 1991
AbstractBone and cartilage formation in the embryo and repair and turnover in the adult involve the progeny of a small number of cells called mesenchymal stem cells. These cells divide, and their progeny become committed to a specific and distinctive phenotypic pathway, a lineage with discrete steps and, finally, end‐stage cells involved with ...
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Stem Cells

2016
This book presents state of the art knowledge regarding the pathophysiology and diagnosis of fecal incontinence and describes and illustrates all relevant treatment techniques. In addition to the approaches that have been the mainstay of treatment of fecal incontinence to date, it covers recent innovations and emerging options, including ...
Ledda M, Giori A, Lisi A
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A stem cell for stem cells in murine haematopoiesis

Nature, 1982
Mature erythrocytes and granulocytes have limited lifespans, do not replicate and must therefore be replenished constantly. They are derived from pluripotent stem cells (PSCs) which are capable of self-renewal1. The numbers and properties of PSCs can be inferred in part from studies of their progeny.
Burton, D I   +3 more
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Stem Cells

Pancreatology, 2007
In this issue, 'Pancreatology and the Web' focuses on stem cell research, one of the 21st century's most exciting areas of science. Stem cell research has been advancing our knowledge about how an organism develops from a single cell and how healthy cells replace damaged cells in adult organisms.
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Neural Stem Cells

2019
Neural stem cell (NSC) transplantation has provided the basis for the development of potentially powerful new therapeutic cell-based strategies for a broad spectrum of clinical diseases, including stroke, psychiatric illnesses such as fetal alcohol spectrum disorders, and cancer.
Tuazon J. P.   +6 more
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