Results 71 to 80 of about 6,619,392 (208)
Creation of a cell culture bank: experience of the Pokrovsky Cell Technology Center
Кардиоваскулярная терапия и профилактикаModern research in cell biology places high demands on the model objects used, including cell cultures. These requirements are dictated by the need to avoid artifacts in work and reduce potential risks to the environment associated with biological hazard.
E. M. Prikhodko +8 more
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The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis
Nature Communications, 2019 LncRNA loci potentially contain multiple modes that can exert function, including DNA regulatory elements. Here, the authors generated genetic models in mice to dissect the role of the syntenically conserved lncRNA Firre in the context of hematopoiesis.
Jordan P. Lewandowski +14 more
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Generation of pancreatic β cells for treatment of diabetes: advances and challenges
Stem Cell Research & Therapy, 2018 Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered attractive sources of pancreatic β cells and islet organoids.
Hussain Md. Shahjalal +4 more
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MicroRNAs, stem cells and cancer stem cells
World Journal of Stem Cells, 2012 This review discusses the various regulatory characteristics of microRNAs that are capable of generating widespread changes in gene expression via post translational repression of many mRNA targets and control self-renewal, differentiation and division of cells.
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FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal [PDF]
, 2012 Drosophila neuroblasts (NBs) have emerged as a model for stem cell biology that is ideal for genetic analysis but is limited by the lack of cell-type-specific gene expression data.
Jonas Steinmann +17 more
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Experimental Biology and Medicine, 2001 Within the bone marrow stroma there exists a subset of nonhematopoietic cells referred to as mesenchymal stem or mesenchymal progenitor cells. These cells can be ex vivo expanded and induced, either in vitro or in vivo, to terminally differentiate into osteoblasts, chondrocytes, adipocytes, tenocytes, myotubes, neural cells, and hematopoietic ...
Minguell, JJ, Erices, A, Conget, P
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From Warnock to the Stem Cell Bank - Evaluating the UK's Regulatory Measures for Stem Cell Research. [PDF]
, 2005 The United Kingdom government regards its regulations for stem cell research as some of the most rigorous in the world. This paper chronologically outlines the important stages in the evolution of these regulatory measures over the past twenty years ...
Twine, Richard, Twine, R.
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Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part II: Gene regulation [PDF]
, 2012 In a mouse model nuclear transfer embryo-derived embryonic stem cell lines (ntESCs) of various genetic backgrounds and donor cell types were compared with reference ESCs and analyzed comprehensively at molecular level as a second part of a larger study ...
Julianna Kobolak +17 more
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Segmental Additive Tissue Engineering
Scientific Reports, 2018 Segmental bone defects caused by trauma and disease represent a major clinical problem worldwide. Current treatment options are limited and often associated with poor outcomes and severe complications. Bone engineering is a promising alternative solution,
Martina Sladkova +8 more
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Journal of Investigative Dermatology Symposium Proceedings, 1997 This article is concerned with the idea that neural precursor cells in vertebrates can self-renew and give rise to all cell types within the nervous system. Supportive evidence for this notion of neural stem cells comes from clonal analyses undertaken both in vivo and in vitro. Neural stem cells also give rise to other cells in the body, including skin
Murphy, M +4 more
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