Results 91 to 100 of about 6,619,392 (208)

Adult limbal neurosphere cells: a potential autologous cell resource for retinal cell generation [PDF]

, 2014
The Corneal limbus is a readily accessible region at the front of the eye, separating the cornea and sclera. Neural colonies (neurospheres) can be generated from adult corneal limbus in vitro.
Jessica Cooke (637632), Jennifer Scott, Heather Thomson, Xiaoli Chen, Lotery, Andrew J., Xiaoli Chen (102563), Cooke, J.J., Scott, Jennifer A., Andrew Lotery, Heather Thomson (637631), Thomson, Heather, Jessica Cooke, Parwez Hossain, Jennifer Scott (637633), Chen, Xiaoli, Hossain, Parwez, Andrew Lotery (637635), Parwez Hossain (637634)   +17 more
core   +1 more source

Subclinical myocardial changes after hematopoietic stem cell transplantation: limited predictive value of early biomarkers and strain imaging

Cardio-Oncology
Background Cardiotoxicity is a relevant late complication after hematopoietic stem cell transplantation. Early identification of subclinical myocardial injury could allow preventive interventions, yet the optimal diagnostic approach in this setting ...
Ana Carolina Oliver, Federico Superchi, Roberto Superchi, Matilde Canabal, Carolina Errecarte, Ricardo Mosquera, Ada Caneiro, Silvia Pierri, Sebastian Galeano, Eloisa Riva, Laura Bello, Regis Gai, Silvana Jubin, Pablo Muxi   +13 more
doaj   +1 more source

Glycolytic enolase 1-induced H4K12 lactylation activates quiescent breast cancer stem-like cells in triple-negative breast cancer

Signal Transduction and Targeted Therapy
Activation of quiescent or extremely slow-cycling breast cancer stem-like cells (qsBCSCs) contributes to tumor progression, yet the regulatory mechanisms involved in triple-negative breast cancer (TNBC) remain elusive. We developed a dual-reporter system
Shuai Liu, Yunfeng Ma, Yujie Zeng, Dekang Lv, Zhijie Hou, Junxiu Huang, Yaqi Gong, Ruijun Feng, Zihan Wang, Ran Sui, Dan Huang, Yameng Wu, Nuo Chen, Mingzhi Yao, Ying Shan, Yuan Huang, Yuesheng Wang, Jinsong Yan, Fei Peng, Quentin Liu, Jie Xu   +20 more
doaj   +1 more source

Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice

Nature Communications, 2016
Rett syndrome is a neurodevelopmental disorder caused by mutations in Mecp2. Here the authors show that Mecp2 loss-of-function leads to upregulation of the NF-κB pathway, and that reducing NF-κB signalling ameliorates phenotypes of Mecp2-null mice, thus ...
Noriyuki Kishi, Jessica L. MacDonald, Julia Ye, Bradley J. Molyneaux, Eiman Azim, Jeffrey D. Macklis   +5 more
doaj   +1 more source

Osteopetrotic induced pluripotent stem cells derived from patients with different disease-associated mutations by non-integrating reprogramming methods

Stem Cell Research & Therapy, 2019
Background Autosomal recessive osteopetrosis is a genetically and phenotypically heterogeneous disease, caused by defects in osteoclast formation and function.
Fatma Visal Okur, İnci Cevher, Cansu Özdemir, Çetin Kocaefe, Duygu Uçkan Çetinkaya   +4 more
doaj   +1 more source

Auxilin regulates intestinal stem cell proliferation through EGFR

, 2022
[[abstract]]Adult tissue homeostasis is maintained by residential stem cells. The proliferation and differentiation of adult stem cells must be tightly balanced to avoid excessive proliferation or premature differentiation.
Zhao, H;Ren, X;Kong, R;Shi, L;Li, Z;Wang, R;Ma, R;Zhao, H;Liu, F;Chang, HC;Chen, CH;Li, Z
core   +1 more source

Generation of footprint-free human induced pluripotent stem cell line (SCIKFi001-B) from cGMP grade umbilical cord-derived mesenchymal stem cells (UC-MSCs) using episomal-plasmid based reprogramming approach

Stem Cell Research
UCMSCs were reprogrammed to iPSCs using Yamanaka factor bearing episomal plasmids. SCIKFi001-B exhibited pluripotency, had typical iPSC morphology and didn’t retain any residual episomal plasmid.
Marchella Tohari, Ricky Sanjaya, Siska Yuliana Sari, Bintang Tedjobagaskara, Andrian Ibnu Faisal, Matheus Alvin Prawira, Anggia Oktaviani Dwi Putri, Naufalia Faza, Harry Murti, Halida P. Widyastuti   +9 more
doaj   +1 more source

SINGLE INTRACAVERNOUS INJECTION OF AUTOLOGOUS ADIPOSE-DERIVED STEM CELLS VERSUS A SINGLE HIGH DOSE OF PLATELET RICH PLASMA TO IMPROVE ERECTILE DYSFUNCTION: A COMPARATIVE STUDY

Continence, 2023
H Bailly, M Abou Chakra, F Schill, B Dabboucy, C Khalil, M Lorenz, N Rodehutskors, J Boaz, M Jida, N El Beayni, K Ismail, E Hanna, L Hage, A Abo Yassine, G Delavar, A Popescu, M Moussa   +16 more
doaj   +1 more source

METTL14 regulates chondrogenesis through the GDF5–RUNX–extracellular matrix gene axis during limb development

Nature Communications
m6A RNA methylation is essential for many aspects of mammalian development but its roles in chondrogenesis remain largely unknown. Here, we show that m6A is necessary for chondrogenesis and limb morphogenesis using limb progenitor-specific knockout mice ...
Nobuko Katoku-Kikyo, Hiroko Kawakami, Max Cantor, Yasuhiko Kawakami, Nobuaki Kikyo   +4 more
doaj   +1 more source

Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells [PDF]

, 2012
Widera D, Hauser S, Kaltschmidt C, Kaltschmidt B. Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells. Anatomy Research International.
Hauser, Stefan, Kaltschmidt, Christian, Widera, Darius, Widera, Darius ; https://orcid.org/, Kaltschmidt, Barbara   +4 more
core   +1 more source