Results 151 to 160 of about 1,144,390 (358)

Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Hold Lower Heterogeneity and Great Promise in Biological Research and Clinical Applications [PDF]

, 2021
Juan Zhang, Mingzhuang Chen, Jinqi Liao, Chongfei Chang, Yuqing Liu, Arshad Ahmed Padhiar, Yan Zhou, Guangqian Zhou   +7 more
openalex   +1 more source

Neural stem cells, neural progenitors, and neurotrophic factors

, 2008
[[abstract]]Neural stem cells (NSCs) have been proposed as a promising cellular source for the treatment of diseases in nervous systems. NSCs can self-renew and generate major cell types of the mammalian central nervous system throughout adulthood.
Hsu, YC; Lee, DC; Chiu, IM
core  

Multilineage differentiation and characterization of the human fetal osteoblastic 1.19 cell line: A possible in vitro model of human mesenchymal progenitors

, 2008
[[abstract]]The in vitro study of human bone marrow mesenchymal stromal cells (BMMSCs) has largely depended on the use of primary cultures. Although these are excellent model systems, their scarcity, heterogeneity, and limited lifespan restrict their ...
Yen, ML; Chien, CC; Chiu, IM; Huang, HI; Chen, YC; Hu, HI; Yen, BL
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Knowledge and attitude regarding stem cell research and its application among medical students in Pakistan [PDF]

, 2020
Mashal Daud, Zaina Sajid, Tooba Ali
openalex   +1 more source

Engineering Stem Cell Organoids

, 2016
Organoid systems leverage the self-organizing properties of stem cells to create diverse multi-cellular tissue proxies. Most organoid models only represent single or partial components of a tissue, and it is often difficult to control the cell type ...
Langer, Robert S, Karp, Jeffrey Michael, Mead, Benjamin Elliott, Levy, Oren, Yin, Xiaolei, Safaee, Helia   +5 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Potent Immunomodulation and Angiogenic Effects of Mesenchymal Stem Cells versus Cardiomyocytes Derived from Pluripotent Stem Cells for Treatment of Heart Failure

, 2018
Heart failure (HF) following myocardial infarction (MI) is the leading cause of mortality and morbidity worldwide. Cell-based therapeutics has been explored as a potential approach to replenish the lost cardiomyocyte and restore cardiac function in HF ...
Lai, WH, Liao, S, Ting, S, Tse, HF, Zhen, Z, Lin, Q, Zhang, YL   +6 more
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Frequency and Implications of High‐Risk Pharmacogenomic Phenotypes Identified in a Diverse Australian Pediatric Oncology Cohort

Clinical and Translational Science
Pharmacogenomics remains underutilized in pediatric oncology, despite the existence of evidence‐based guidelines. Implementation of pharmacogenomics‐informed prescribing could improve medication safety and efficacy in pediatric oncology patients, who are
Claire Moore, Andreas Halman, Tayla Stenta, Dhrita Khatri, Elizabeth Williams, Roxanne Dyas, Julian Stolper, David A. Elliott, Rachel Conyers   +8 more
doaj   +1 more source