Results 41 to 50 of about 8,398,186 (316)

Stem Cell Therapy for the Heart [PDF]

Congestive Heart Failure, 2004
Cellular cardiomyoplasty is an expanding field of research that involves numerous types of immature cells administered via several modes of delivery. The purpose of this review is to investigate the benefits of different types of cells used in stem cell research as well as the most efficient mode of delivery. The authors also present data showing that
Loren E, Wold, Wangde, Dai, Casilde, Sesti, Sharon L, Hale, Joan S, Dow, Bradley J, Martin, Robert A, Kloner   +6 more
openaire   +2 more sources

Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting [PDF]

, 2012
INTRODUCTION: Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However, recently it has become clear that only
Van der Linden, Annemie, Herman Goossens, Annemie Van der Linden, De Vocht, Nathalie, Debbie Le Blon, Hoornaert, Chloé, Kristien Reekmans, Berneman, Zwi, Jasmijn Daans, Reekmans, Kristien, Nathalie De Vocht, Ponsaerts, Peter, Fransen, Erik, Chloé Hoornaert, Hoornaert, Chlo\ue9, Erik Fransen, Praet, Jelle, Le Blon, Debbie, Zwi Berneman, Goossens, Herman, Peter Ponsaerts, Jelle Praet, Daans, Jasmijn   +22 more
core   +1 more source

Brief Report: The lincRNA Hotair Is Required for Epithelial-to-Mesenchymal Transition and Stemness Maintenance of Cancer Cell Lines

, 2013
Hotair is a member of the recently described class of noncoding RNAs called lincRNA (large intergenic noncoding RNA). Various studies suggest that Hotair acts regulating epigenetic states by recruiting chromatin-modifying complexes to specific target ...
Fonseca, Aline Simoneti, Alves, Cleidson Padua, Buerger, Matheus Carvalho, Souza, Jorge E. S. de, Valente, Valeria [UNESP], Silva, Wilson Araujo, Bueno, Rafaela de Barros e Lima, Valente, Valeria, Muys, Bruna Rodrigues, Zago, Marco Antonio   +9 more
core   +1 more source

Notch promotes neural lineage entry by pluripotent embryonic stem cells [PDF]

, 2006
A central challenge in embryonic stem (ES) cell biology is to understand how to impose direction on primary lineage commitment. In basal culture conditions, the majority of ES cells convert asynchronously into neural cells.
Smith, Austin G, Austin G Smith, Heavey Barry, Alexandra Benchoua, Benchoua, Alexandra, Smith, Austin,, Benchoua Alexandra, Sally Lowell, Smith Austin G, Lowell, Sally; id_orcid, Smith, Austin, G., Lowell Sally, Lowell, Sally, Heavey, Barry, Barry Heavey   +14 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Cardiac Stem Cell Therapy and the Promise of Heart Regeneration

, 2013
Stem cell therapy for cardiac disease is an exciting but highly controversial research area. Strategies such as cell transplantation and reprogramming have demonstrated both intriguing and sobering results.
Garbern, Jessica, Lee, Richard
core   +1 more source

Neural crest-derived stem cells [PDF]

, 2010
The neural crest is a transient embryonic structure in vertebrates that gives rise to most of the peripheral nervous system (PNS) and to several non-neural cell types, including smooth muscle cells of the cardiovascular system, pigment cells in the skin,
Sommer, L, Shakhova, O
core   +1 more source

Stem cell therapy independent of stemness

World Journal of Stem Cells, 2012
Mesenchymal stem cell (MSC) therapy is entering a new era shifting the focus from initial feasibility study to optimization of therapeutic efficacy. However, how MSC therapy facilitates tissue regeneration remains incompletely characterized. Consistent with the emerging notion that secretion of multiple growth factors/cytokines (trophic factors) by MSC
openaire   +2 more sources

Stem Cell Therapy in PAD [PDF]

European Journal of Vascular and Endovascular Surgery, 2010
Critical limb ischemia (CLI) continues to form a substantial burden on Western health care. Despite recent advances in surgical and radiological vascular techniques, a large number of patients is not eligible for these revascularisation procedures and faces amputation as their ultimate treatment option.
Sprengers, R. W., Moll, F. L., Verhaar, M. C.   +2 more
openaire   +3 more sources

Combined lentiviral- and RNA-mediated CRISPR/Cas9 delivery for efficient and traceable gene editing in human hematopoietic stem and progenitor cells

Scientific Reports, 2020
The CRISPR/Cas9 system is a versatile tool for functional genomics and forward genetic screens in mammalian cells. However, it has been challenging to deliver the CRISPR components to sensitive cell types, such as primary human hematopoietic stem and ...
David Yudovich, Alexandra Bäckström, Ludwig Schmiderer, Kristijonas Žemaitis, Agatheeswaran Subramaniam, Jonas Larsson   +5 more
doaj   +1 more source