Results 21 to 30 of about 8,398,186 (316)

Enhancing the efficacy of stem cell therapy with glycosaminoglycans [PDF]

, 2020
Human mesenchymal stem cell (hMSC) therapy offers significant potential for osteochondral regeneration. Such applications require their ex vivo expansion in media frequently supplemented with fibroblast growth factor 2 (FGF2). Particular heparan sulfate (
Smith, Raymond A. A., Cool, Simon M., Tan, Clarissa L. L., Eio, Michelle, Sathiyanathan, Padmapriya, Nurcombe, Victor, van Wijnen, Andre J., Mah, Sophia, Hui, James H., Cao, Xue, Raghunath, Michael, Ren, Xiafei, Hassan, Afizah Binte Mohd, Samsonraj, Rebekah M., Ling, Ling   +14 more
core   +1 more source

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection [PDF]

, 2009
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D., Chiu Sum Ying, Brian C Beard, Robert A Wu, John J Rossi, Muñoz Nina M., Nina M Muñoz, John J. Rossi, Brian C. Beard, Dorothee von Laer, Laer, Dorothee von, Grant D Trobridge, Beard Brian C., Chiu, Sum Ying, Nina M. Muñoz, Kiem, Hans-Peter, Sum Ying Chiu, Trobridge Grant D., Wu, Robert A., Hans-Peter Kiem, Kiem Hans-Peter, Beard, Brian C., Wu Robert A., von Laer Dorothee, Rossi, John J., Rossi John J., Grant D. Trobridge, Robert A. Wu, Muñoz, Nina M.   +28 more
core   +2 more sources

Stem Cells and Stem Cell Therapy

MedEdPORTAL, 2013
Abstract This team-based learning (TBL) exercise presents hematopoietic malignancies of myeloid origin and invites users to consider appropriate methods of treatment utilizing stem cell therapy. The 100-minute session is structured in traditional TBL format, and all components—including the learning objectives, reading assignments, individual Readiness
Adam Gromley, Zeynep Gromley
openaire   +2 more sources

Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]

, 2009
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J, Aldskogius, Hakan, Wegner, M, Hjerling-Leffler, Jens, Kozlova, Elena N, Medvinsky, Alexander, Berens, C, Aldskogius, H, Kozlova, EN, Berens, Christian, Kanaykina, Nadezda, Sandelin, Martin, Schreiner, S, Wegner, Michael, Kanaykina, N, Sandelin, M, Liakhovitskaia, A, Medvinsky, A, Liakhovitskaia, Anna, Schreiner, Silke, Kanaykina, Nadegda,, Kozlova, Elena,, Aldskogius, Håkan,, Sandelin, Martin,, Berens, Christian,   +24 more
core   +1 more source

Stem Cell Plasticity and Issues of Stem Cell Therapy

Folia Biologica, 2005
Today, there is much evidence suggesting that organ-specific stem cells need not rely completely on their own sources for maintenance and regeneration of an organism. In certain circumstances, mostly related to tissue damage, stem cell populations residing past the affected organ can contribute to its recovery that means from ...
S, Filip, J, Mokrý, D, English, J, Vojácek   +3 more
openaire   +2 more sources

Stem cell therapy in dermatology

Indian Journal of Dermatology, Venereology and Leprology, 2021
Stem cells are precursor cells present in many tissues with ability to differentiate into various types of cells. This interesting property of plasticity can have therapeutic implications and there has been substantial research in this field in last few decades.
Sujay, Khandpur, Savera, Gupta, D R, Gunaabalaji   +2 more
openaire   +3 more sources

Stem Cells for Heart Cell Therapies

Tissue Engineering Part B: Reviews, 2008
Myocardial infarction-induced heart failure is a prevailing cause of death in the United States and most developed countries. The cardiac tissue has extremely limited regenerative potential, and heart transplantation for reconstituting the function of damaged heart is severely hindered mainly due to the scarcity of donor organs. To that end, stem cells
Donghui, Jing, Abhirath, Parikh, John M, Canty, Emmanuel S, Tzanakakis   +3 more
openaire   +3 more sources

Stem cells: sources and therapies [PDF]

Biological Research, 2012
The historical, lexical and conceptual issues embedded in stem cell biology are reviewed from technical, ethical, philosophical, judicial, clinical, economic and biopolitical perspectives. The mechanisms assigning the simultaneous capacity to self-renew and to differentiate to stem cells (immortal template DNA and asymmetric division) are evaluated in ...
Monti M, Perotti C, Del Fante C, Cervio M, REDI, CARLO ALBERTO   +4 more
openaire   +6 more sources

Gene and Stem Cell Therapies [PDF]

JAMA, 2001
Gene and stem cell therapies hold promise for the treatment of a wide variety of inherited and acquired human diseases. Identification of genes involved in human disease and development of novel vectors and devices for delivering therapeutic genes to different tissues in vivo have resulted in significant progress in the area of gene therapy.
E H, Kaji, J M, Leiden
openaire   +2 more sources

Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells

Haematologica, 2022
Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence.
Sarah Warsi, Maria Dahl, Emma M. K. Smith, Anna Rydstrom, Els Mansell, Valgardur Sigurdsson, Julia Sjoberg, Shamit Soneji, Emma Rorby, Kavitha Siva, Tan H. M. Grahn, Yang Liu, Ulrika Blank, Goran Karlsson, Stefan Karlsson   +14 more
doaj   +1 more source