Results 141 to 150 of about 333,760 (309)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

"The antibiotic paradox" in allogeneic stem cell transplantation. [PDF]

Bone Marrow Transplant
Weber D, Meedt E, Ghimire S, Hiergeist A, Kern MAG, Höpting M, Thiele Orberg E, Shaikh H, Beilhack A, Wolff D, Edinger M, Herr W, Gessner A, Poeck H, Holler E.   +14 more
europepmc   +1 more source

Allogeneic Hematopoietic Stem Cell Transplant for Adults over 40 Years Old with Acquired Aplastic Anemia

, 2012
Hawk Kim, Kyoo‐Hyung Lee, Sung‐Soo Yoon, Sang Kyun Sohn, Young Don Joo, Sung Hyun Kim, Byung Soo Kim, Jung Hye Choi, Jae Youg Kwak, Myung Soo Hyun, Sung Hwa Bae, Ho Jin Shin, Jong-Ho Won, Sukjoong Oh, Won Sik Lee, Jae-Hoo Park, Chul Won Jung   +16 more
openalex   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Allogeneic hematopoietic stem cell transplantation for the treatment of chronic active Epstein-Barr virus infection. [PDF]

Cell Transplant
Wang Y, Wu J, Huang X, Xiao Y.
europepmc   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

Advanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei, Luping Wang, Haitong Jing, Xian Qin, Jiong‐Wei Wang, Xiaogang Liu   +5 more
wiley   +1 more source

Utility and Safety of Romiplostim in Pediatric Allogeneic Stem Cell Transplantation. [PDF]

Pediatr Transplant
Senthil S, Moothedath A, Potter JE, Wilkinson HM, Whiteside E, Nataraj R, Mustafa O, Horgan C, Bonney D, Brett S, Wynn R.   +10 more
europepmc   +1 more source

Induction of Human Wharton’s Jelly of Umbilical Cord Derived Mesenchymal Stem Cells to Be Chondrocytes and Transplantation in Guinea Pig Model with Spontaneous Osteoarthritis [PDF]

Gulrez Nadeem, Kasem Theerakittayakorn, Sirilak Somredngan, Nguyễn Thị Hồng, Traimat Boonthai, Worawalan Samruan, Ponthep Tangkanjanavelukul, Rangsun Parnpai   +7 more
openalex   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source