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Allogeneic Stem Cell Transplantation
Transplantation Proceedings, 2005Allogeneic stem cell transplantation (HSCT) requires the harvest of an adequate number of stem cells (SC) from a histocompatible donor and their infusion into a patient following a conditioning regimen. During the past 35 years, the role of HSCT has changed from an experimental procedure for terminally ill patients to a curative treatment.
BOSI, ALBERTO, BARTOLOZZI B, GUIDI S.
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Limbal Stem-Cell Transplantation
International Ophthalmology Clinics, 1999Cornea epithelium is subject to constant trauma and shedding of the surface epithelium, and replenishment is from epithelial cells beneath and peripheral to the central desquamating epithelium. The origin of the corneal epithelium appears to reside in the crypts of Vogt, where a population of "immortal" stem cells resides, possessing enormous potential
E K, Akpek, C S, Foster
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Fetal stem-cell transplantation
Best Practice & Research Clinical Obstetrics & Gynaecology, 2008Fetal stem-cell transplantation is an attractive approach to the treatment of a variety of hematological, metabolic and immunological diseases before birth. The possibility of delivering a large number of cells in an early stage of life, and of taking advantage of normal fetal stem-cell migration and development, is promising.
Eleonor, Tiblad, Magnus, Westgren
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Intestinal stem cell transplantation
Journal of Gastroenterology, 2016Organoid technologies to expand intestinal epithelial cells are gaining increasing attention as a useful tool to investigate many aspects of intestinal epithelial biology and pathology. One important application of organoid systems would be to use intestinal epithelial cells expanded in culture for following transplantation experiments. In this article,
Tetsuya, Nakamura, Mamoru, Watanabe
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Hematopoietic Stem Cell Transplantation
Hospital Practice, 1993The isolation, purification, and in vitro expansion of the hematopoietic stem cell have allowed pretransplant immunologic and genetic manipulation. As a result, rapid allogeneic or autologous hematologic reconstitution with minimal graft-versus-host disease is possible in patients receiving high-dose chemotherapy.
S, Jagannath, B, Barlogie, G, Tricot
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Stem Cell Transplantation Methods
2010Just a few short years ago, we still used to think that we were born with a finite number of irreplaceable neurons. However, in recent years, there has been increasingly persuasive evidence that suggests that neural stem cell (NSC) maintenance and differentiation continue to take ace throughout the mammal's lifetime.
Kimberly D, Tran +2 more
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Spermatogonial stem cell transplantation
Molecular and Cellular Endocrinology, 2000The development of the spermatogonial transplantation technique has given new impetus to research on spermatogonial stem cells. Possibilities opened by this technique include: (a) New ways to study fundamental aspects of spermatogenesis; (b) Generation of transgenic large domestic animals; (c) Protection of (young) male cancer patients from infertility
Izadyar, F. +4 more
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Stem Cell Transplantation (Cord Blood Transplants)
Hematology, 2004AbstractAllogeneic stem cell transplantation is an accepted treatment modality for selected malignant and non-malignant diseases. However, the ability to identify suitably matched related or unrelated donors can be difficult in some patients. Alternative sources of stem cells such as cord blood provide a readily available graft for such patients.
Nelson J, Chao +2 more
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Mesenchymal Stem Cells and Hematopoietic Stem Cell Transplantation
Annals of the New York Academy of Sciences, 2003Abstract: Techniques have recently beome available to isolate and grow mesenchymal progenitors and to manipulate their growth under defined in vitro culture conditions. As a result mesenchymal stem cells can be rapidly expanded to numbers that are required for clinical application.
Willem E, Fibbe, Willy A, Noort
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Hematopoietic Stem-Cell Transplantation
New England Journal of Medicine, 2006Hematopoietic stem-cell transplantation, which is used to treat both malignant and nonmalignant conditions, was first conceived more than 50 years ago, but problems associated with transplanting a nonsolid organ and modulating the immune response had to be solved before the procedure could be used clinically.
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