Results 41 to 50 of about 1,446,025 (307)

Targeting autophagy increases the efficacy of proteasome inhibitor treatment in multiple myeloma by induction of apoptosis and activation of JNK

BMC Cancer, 2022
Background The therapeutic armamentarium in multiple myeloma has been significantly broadened by proteasome inhibitors, highly efficient means in controlling of multiple myeloma.
Azam Salimi, Kema Marlen Schroeder, Mirle Schemionek-Reinders, Margherita Vieri, Saskia Maletzke, Deniz Gezer, Behzad Kharabi Masouleh, Iris Appelmann   +7 more
doaj   +1 more source

Selection of Suitable Alternative Donor in the Absence of Matched Sibling Donor: A Retrospective Single-Center Study to Compare between Haploidentical, 10/10 and 9/10 Unrelated Donor Transplantation

International Journal of Hematology-Oncology and Stem Cell Research, 2021
Background: Finding a suitable donor at the optimal time is one of the most challenging issues in many transplant centers. We evaluated the clinical outcomes of 248 patients with acute leukemia and without matched sibling donors (MSD) who underwent ...
Maryam Barkhordar, Amir Kasaeian, Seied Asadollah Mousavi, Sahar Tavakoli, Mohammad Vaezi, Hosein Kamranzadeh Foumani, Tanaz Bahri, Davood Babakhani, Leila Mirzakhani, Ashraf Mousavi, Ardeshir Ghavamzadeh   +10 more
doaj   +1 more source

A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency [PDF]

, 2019
Producción CientíficaOcular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive and/or severe limbal stem cell deficiencies that lead to corneal epithelial ...
Alberca Zaballos, Mercedes, Calonge Cano, Margarita, Fernández Martínez, Itziar, Galindo de la Rosa, Sara, García-Sancho Martín, Francisco Javier, Herreras Cantalapiedra, José María, López Paniagua, Marina, Nieto Miguel, Teresa, Pérez Soto, María Inmaculada, Sánchez García, Ana María de los Ángeles   +9 more
core   +2 more sources

Finding the Optimal Conditioning Regimen for Relapsed/Refractory Lymphoma Patients Undergoing Autologous Hematopoietic Cell Transplantation: A Retrospective Comparison of BEAM and High-Dose ICE

Turkish Journal of Hematology, 2016
Objective: High-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (AHCT) is a well-defined treatment modality for relapsed/refractory non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL).
Onur Esbah, Emre Tekgündüz, Itır Şirinoğlu Demiriz, Sinem Civriz Bozdağ, Ali Kaya, Ayşegül Tetik, Ömür Kayıkçı, Gamze Durgun, Şerife Kocubaba, Fevzi Altuntaş   +9 more
doaj   +1 more source

A general practitioner's guide to hematopoietic stem-cell transplantation.

Current Oncology, 2019
Hematopoietic stem-cell transplantation (hsct) is a medical procedure that consists of infusing stem cells after a short course of chemotherapy or radiotherapy, or both.
A. Bazinet, G. Popradi
semanticscholar   +1 more source

Stem Cells and Transplant Arteriosclerosis [PDF]

Circulation Research, 2008
Stem cells can differentiate into a variety of cells to replace dead cells or to repair damaged tissues. Recent evidence indicates that stem cells are involved in the pathogenesis of transplant arteriosclerosis, an alloimmune initiated vascular stenosis that often results in transplant organ failure.
openaire   +4 more sources

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. [PDF]

, 2017
A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs) from pluripotent cells was ...
Chen, Di, Clark, Amander T, Hennebold, Jon D, Lam, Truong N, Meistrich, Marvin L, Mitchell, Jennifer M, Orwig, Kyle E, Peters, Karen A, Rojas, Ernesto J, Shetty, Gunapala, Sosa, Enrique, Sukhwani, Meena, Tailor, Ramesh C, Wu, Zhuang   +13 more
core   +2 more sources

Neural stem cell transplantation therapy for brain ischemic stroke: Review and perspectives

World Journal of Stem Cells, 2019
Brain ischemic stroke is one of the most common causes of death and disability, currently has no efficient therapeutic strategy in clinic. Due to irreversible functional neurons loss and neural tissue injury, stem cell transplantation may be the most ...
Guilong Zhang, Zhijun Zhu, Ye-Zhong Wang
semanticscholar   +1 more source

Hematopoietic stem cells for transplantation [PDF]

Nature Immunology, 2002
Multiple sources of HSCs exist. Here, Verfaillie discusses the long-term engraftment capabilities of each source and the search for ex vivo expansion conditions to allow bulk culture for therapeutic HSC transplantation.
openaire   +4 more sources

Nanopore sequencing approach for immunoglobulin gene analysis in chronic lymphocytic leukemia

Scientific Reports, 2021
The evaluation of the somatic hypermutation of the clonotypic immunoglobulin heavy variable gene has become essential in the therapeutic management in chronic lymphocytic leukemia patients.
Crescenzio Francesco Minervini, Cosimo Cumbo, Immacolata Redavid, Maria Rosa Conserva, Paola Orsini, Antonella Zagaria, Luisa Anelli, Nicoletta Coccaro, Giuseppina Tota, Luciana Impera, Elisa Parciante, Francesco Tarantini, Annamaria Giordano, Giorgina Specchia, Pellegrino Musto, Francesco Albano   +15 more
doaj   +1 more source