Turkish Journal of Hematology, 2016 Objective: High-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (AHCT) is a well-defined treatment modality for relapsed/refractory non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL).
Onur Esbah +9 more
doaj +1 more source
Graphene for Controlled and Accelerated Osteogenic Differentiation of Human Mesenchymal Stem Cells [PDF]
ACS Nano 5, 4670-4678 (2011), 2011 Modern tissue engineering strategies combine living cells and scaffold materials to develop biological substitutes that can restore tissue functions. Both natural and synthetic materials have been fabricated for transplantation of stem cells and their specific differentiation into muscles, bones and cartilages.
arxiv +1 more source
Neural stem cell transplantation therapy for brain ischemic stroke: Review and perspectives
World Journal of Stem Cells, 2019 Brain ischemic stroke is one of the most common causes of death and disability, currently has no efficient therapeutic strategy in clinic. Due to irreversible functional neurons loss and neural tissue injury, stem cell transplantation may be the most ...
Guilong Zhang, Zhijun Zhu, Ye-Zhong Wang
semanticscholar +1 more source
Stem Cells and Transplant Arteriosclerosis [PDF]
Circulation Research, 2008 Stem cells can differentiate into a variety of cells to replace dead cells or to repair damaged tissues. Recent evidence indicates that stem cells are involved in the pathogenesis of transplant arteriosclerosis, an alloimmune initiated vascular stenosis that often results in transplant organ failure.
openaire +4 more sources
Polymorphism in TGFB1 is associated with worse non-relapse mortality and overall survival after stem cell transplantation with unrelated donors. [PDF]
, 2015 Transforming growth factor beta-1, encoded by the TGFB1 gene, is a cytokine that plays a central role in many physiological and pathogenic processes.
Apperley, JF +13 more
core +2 more sources
Blood, 2017 Despite advances in supportive therapy to prevent complications of sickle cell disease (SCD), access to care is not universal. Hematopoietic cell transplantation is, to date, the only curative therapy for SCD, but its application is limited by ...
E. Gluckman +35 more
semanticscholar +1 more source
Micro- and nanoengineering approaches to control stem cell-biomaterial interactions. [PDF]
, 2011 As our population ages, there is a greater need for a suitable supply of engineered tissues to address a range of debilitating ailments. Stem cell based therapies are envisioned to meet this emerging need. Despite significant progress in controlling stem
Dokmeci, Mehmet R +4 more
core +2 more sources
Development of a protocol for maintaining viability while shipping organoid-derived retinal tissue. [PDF]
, 2020 Retinal organoid technology enables generation of an inexhaustible supply of three-dimensional retinal tissue from human pluripotent stem cells (hPSCs) for regenerative medicine applications.
Binette, Francois +6 more
core +1 more source
Stem Cell Transplantation As A Dynamical System: Are Clinical Outcomes Deterministic? [PDF]
Frontiers in Immunology (2014). 5:613, 2014 Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However the clinical course following SCT appears to demonstrate many characteristics of dynamical systems, especially when outcomes are considered in the context of immune reconstitution.
arxiv +1 more source
Survival Prediction of Children Undergoing Hematopoietic Stem Cell Transplantation Using Different Machine Learning Classifiers by Performing Chi-squared Test and Hyper-parameter Optimization: A Retrospective Analysis [PDF]
, 2022 Bone Marrow Transplant, a gradational rescue for a wide range of disorders emanating from the bone marrow, is an efficacious surgical treatment. Several risk factors, such as post-transplant illnesses, new malignancies, and even organ damage, can impair long-term survival. Therefore, technologies like Machine Learning are deployed for investigating the
arxiv +1 more source