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Nature Reviews Molecular Cell Biology, 2021
Sara Wickstrom draws attention to the pioneering work of Watt, Jordan and O’Neill on the role of cell shape in the regulation of stem cells.
Clementine Villeneuve +2 more
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Sara Wickstrom draws attention to the pioneering work of Watt, Jordan and O’Neill on the role of cell shape in the regulation of stem cells.
Clementine Villeneuve +2 more
exaly +4 more sources
The effect of mesenchymal stem cell shape on the maintenance of multipotency
Biomaterials, 2013Human mesenchymal stem cells (MSCs) have broad therapeutic potential due to their ability to differentiate into multiple cell types. However, when cultured ex vivo MSCs will spontaneously differentiate and have been shown to lose multipotency after prolonged passaging.
Douglas Zhang, Kristopher A Kilian
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Nature Materials, 2016
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Bettina Weigelin, Peter Friedl
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Bettina Weigelin, Peter Friedl
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Shaping the Future with STEM Instruction
2020This book builds on an interdisciplinary approach that combines two or more of the STEM subjects. The goal is to help students see the relationship among science, technology, engineering, and mathematics. Useful ideas, activities, and lesson plans are part of the package.
Dennis Adams, Mary Hamm
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The Mach stem phenomenon for shaped obstacles buried in soil
Advances in Engineering Software, 2014The paper investigates the explosion characteristics of a below ground event of an explosive charge in proximity to a rigid cylindrical obstacle. The two-dimensional study simulates a line explosive and a parallel long cylindrical structure. The investigation shows that the unloading branch has a negligible effect on the peak pressure envelope whereas ...
Y. S. Karinski +3 more
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Cancer Stemness as a Target for Immunotherapy is Shaped by Proinflammatory Stress
Current Stem Cell Research & Therapy, 2021Cancer stem cells represent a rare subpopulation of cancer cells carrying self-renewal and differentiation features in multi-step tumorigenesis, tumor recurrence and metastasis. Proinflammatory stress is highly associated with cancer stemness via induction of cytokines, tumorpromoting immune cells and cancer stemness-related signaling pathways.
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American Midland Naturalist, 1971
Based on experiment, functional relationships are found that give, with considerable precision, the loading, the normal stress and the radius as a function of stem height. Using the functional relationship for the loading and for the normal stress, a theoretical expression for the radius distribution in the stem and for the volume of the stem is ...
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Based on experiment, functional relationships are found that give, with considerable precision, the loading, the normal stress and the radius as a function of stem height. Using the functional relationship for the loading and for the normal stress, a theoretical expression for the radius distribution in the stem and for the volume of the stem is ...
openaire +1 more source
Control of the epithelial stem cell epigenome: the shaping of epithelial stem cell identity
Current Opinion in Cell Biology, 2013The squamous epithelium covering the skin and oral mucosa relies on epithelial stem cells for tissue renewal. Dynamic changes in DNA methylation, histone methylation and acetylation, and higher order chromatin structure are required to preserve their self-renewal capacity while orchestrating the timely execution of cell differentiation programs.
Ramiro, Iglesias-Bartolome +2 more
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An Automically Shaped Prothesis Stem
2004≫We had these beautiful implants that were made to fit the individual extremely accurately. We had also broaches that were the same sizes as the implant… but then we had to take a 2 1/2 lb mallet and ram it down the bone in order to cut inside of the bone out.
James B. Stiehl +2 more
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