Results 91 to 100 of about 216,025 (255)

Effect of the stage of maturity on the leaf percentage of lucerne and the effect of additives on silage characteristics

open access: yesCzech Journal of Animal Science, 2008
The first part of the study concerns the effect of the stage of maturity on nutrient content and leaf percentage of lucerne (Medicago sativa). The plants of lucerne were harvested and analysed at several stages of growth.
Y. Tyrolová, A. Výborná
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Sources of Nutrients for the Growing Ear of Winter Wheat in the Critical Cereal Window

open access: yesAgronomy
The process of winter bread wheat (WW) nutrient management in the Critical Cereal Window (CCW) has a decisive impact on yield component formation and, consequently, the grain yield (GY) and grain protein content (GPC).
Witold Grzebisz   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Femoral stem wear in cemented total hip replacement [PDF]

open access: yes, 2008
The great success of cemented total hip replacement to treat patients with end-stage osteoarthritis and osteonecrosis has been well documented. However, its long-term survivorship has been compromised by progressive development of aseptic loosening, and ...
Barrans, Simon   +16 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Secondary cell wall composition and candidate gene expression in developing willow (Salix purpurea) stems [PDF]

open access: yes, 2014
The properties of the secondary cell wall (SCW) in willow largely determine the suitability of willow biomass feedstock for potential bioenergy and biofuel applications.
Keywan Hassani-Pak   +21 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Assessment of Charge Dilution Strategies to Reduce Fuel Consumption in Natural Gas-Fuelled Heavy-Duty Spark Ignition Engines

open access: yesEnergies
The need to decarbonize the road transport sector is driving the evaluation of alternative solutions. From a long-term perspective, biomethane and e-methane are particularly attractive as green energy carriers and a part of the solutions for the ...
Davide Di Domenico   +3 more
doaj   +1 more source

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