Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Secondary structures in polyoma DNA [PDF]
Three reproducible secondary-structure features were observed on single strands of polyoma virus DNA mounted for electron microscopy by the T4 gene 32 protein technique: (i) a hairpin fold-back extending from 92.9 +/- 0.8 to 95.0 +/- 0.7 map units; (ii ...
Davidson, Norman +2 more
core
An experimental evaluation of cattail (Typha spp.) cutting depths on subsequent regrowth [PDF]
Citation: Moorberg, C. & Ahlers, A. (2020). An experimental evaluation of cattail (Typha spp.) cutting depths on subsequent regrowth.Cattail (Typha spp.) expansions can negatively affect both native wetland flora and fauna diversity, and active ...
Ahlers, Adam A, Moorberg, Colby J.
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Sources of Nutrients for the Growing Ear of Winter Wheat in the Critical Cereal Window
The process of winter bread wheat (WW) nutrient management in the Critical Cereal Window (CCW) has a decisive impact on yield component formation and, consequently, the grain yield (GY) and grain protein content (GPC).
Witold Grzebisz +4 more
doaj +1 more source
Evaluation by Foster Parents of Services Received from The Children’s Aid Society of Metropolitan Toronto [PDF]
The problem area is evaluation of service by foster parents. My concern with this problem stems first from a general concern for what recipients of service value or devalue in that service. There is sparse available data in this area. John E.
Allen, Barbara
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Timescales distribution and reactive structures in MILD reactors for different energy carriers
Moderate or Intense Low-oxygen Dilution (MILD) combustion processes are purported to be fuel-flexible, thus offering a real opportunity to use a large palette of fuels.
Giovanni Battista Ariemma +5 more
doaj +1 more source

