Results 111 to 120 of about 1,497,400 (281)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Assessment of Charge Dilution Strategies to Reduce Fuel Consumption in Natural Gas-Fuelled Heavy-Duty Spark Ignition Engines

Energies
The need to decarbonize the road transport sector is driving the evaluation of alternative solutions. From a long-term perspective, biomethane and e-methane are particularly attractive as green energy carriers and a part of the solutions for the ...
Davide Di Domenico, Pierpaolo Napolitano, Dario Di Maio, Carlo Beatrice   +3 more
doaj   +1 more source

Efeito do ataque de Alabama argillacea no crescimento vegetativo e sua relação com a fenologia do algodoeiro Effect of Alabama argillacea attack on vegetative growth and its relationship with cotton phenology

Pesquisa Agropecuária Brasileira, 2001
O objetivo deste trabalho foi estudar o efeito do ataque do curuquerê (Alabama argillacea Hübner, 1818), no desenvolvimento vegetativo do algodoeiro e sua relação com a fenologia da planta.
Ednaldo da Silva Quirino, José Janduí Soares   +1 more
doaj   +1 more source

Risk management and the stratification of logistics service provision [PDF]

, 2011
This paper stems from a research project undertaken between 2007 and 2010. It discusses the development of supply chain management together with the understanding of the impact of supply chain risk. It gives an overview of the increasing stratification
Gibson, R., Maden, Will, Savage, Christopher J., Slater, Alan   +3 more
core  

Stem cell therapy independent of stemness

World Journal of Stem Cells, 2012
Mesenchymal stem cell (MSC) therapy is entering a new era shifting the focus from initial feasibility study to optimization of therapeutic efficacy. However, how MSC therapy facilitates tissue regeneration remains incompletely characterized. Consistent with the emerging notion that secretion of multiple growth factors/cytokines (trophic factors) by MSC
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A Hybrid Energy System Based on Externally Fired Micro Gas Turbines, Waste Heat Recovery and Gasification Systems: An Energetic and Exergetic Performance Analysis

Energies
The opportunities related to the adoption of synthetic gaseous fuels derived from solid biomass are limited by the issues caused by the peculiarities of the syngas. The aim of this paper is to analyze several possible layouts of hybrid energy systems, in
Fabrizio Reale, Patrizio Massoli
doaj   +1 more source

Nestedness in mutualistic networks [PDF]

, 2013
James et al. (2012) presented simulations that apparently falsify the analytical result by Bastolla et al. (2009), who showed that nested mutualistic interactions decrease interspecific competition and increase biodiversity in model ecosystems.
Bascompte, Jordi, Fortuna, Miguel A., Luque, Bartolo, Rohr, Rudolf P.   +3 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Descripción anatómica vegetativa de dos especies de Nymphoides (Menyanthaceae) Vegetative anatomy of two Nymphoides species (Menyanthaceae)

Revista Mexicana de Biodiversidad, 2006
En México crecen dos especies de Nymphoides, N. indica y N. fallax. El conocimiento de la anatomía del género es incompleto y N. fallax no se ha tratado.
Mahinda Martínez, Maricela Gómez Sánchez   +1 more
doaj