Results 71 to 80 of about 936,083 (392)

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Carotid artery disease screening : assessment of criteria [PDF]

, 1996
The Department of Radiology at St. Luke’s Hospital has provided a screening service for stroke related disease since April 1991. This consisted of Duplex Ultrasound screening (DUS) for Extracranial Carotid Artery Disease (ECAD) followed by angiography or
Galea Debono, Anthony, Gatt, Alexander, Zammit, Anthony   +2 more
core  

MRI-based Surgical Planning for Lumbar Spinal Stenosis

, 2017
The most common reason for spinal surgery in elderly patients is lumbar spinal stenosis(LSS). For LSS, treatment decisions based on clinical and radiological information as well as personal experience of the surgeon shows large variance.
Andrew J. Haig, F Pedregosa, Gustav Andreisek, J Duchi, James N. Weinstein, Jon D. Lurie, Maureen C. Jensen, Michael C. Fu, RA Deyo, W W Downie, Y LeCun, Y. Ishimoto, Zareth N. Irwin   +12 more
core   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

Transcatheter aortic-valve replacement for inoperable severe aortic stenosis.

New England Journal of Medicine, 2012
BACKGROUND Transcatheter aortic-valve replacement (TAVR) is the recommended therapy for patients with severe aortic stenosis who are not suitable candidates for surgery. The outcomes beyond 1 year in such patients are not known.
R. Makkar, G. Fontana, H. Jilaihawi, S. Kapadia, A. Pichard, P. Douglas, V. Thourani, V. Babaliaros, J. Webb, H. Herrmann, J. Bavaria, S. Kodali, David L. Brown, B. Bowers, T. Dewey, L. Svensson, M. Tuzcu, J. Moses, Matthew R. Williams, R. Siegel, J. Akin, W. Anderson, S. Pocock, Craig R. Smith, M. Leon   +24 more
semanticscholar   +1 more source

Novel Drug‐Testing Platform for Vascular Injury‐induced Intimal Hyperplasia Using a Microphysiological System

Advanced Healthcare Materials, EarlyView.
This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam, HyeMi Kim, Jeong Ah Kim, Ki‐Hwan Nam, Kye‐Sung Lee, Hwan Hur, Jessie S. Jeon, Ji Yong Bae   +7 more
wiley   +1 more source

Use of Lithotripsy in a Calcified Saphenous Vein Graft

JACC: Case Reports, 2020
Percutaneous coronary interventions in saphenous vein grafts can pose a variety of challenges, such as severely calcified lesions. If these lesions are nondilatable, lithotripsy can arguably be a proper tool for lesion preparation.
Menno van Gameren, MD, PhD, Jeroen Vos, MD, PhD, Alexander J.J. IJsselmuiden, MD, PhD, Ben J.L. Van den Branden, MD, PhD, Martijn Meuwissen, MD, PhD, Peter den Heijer, MD, PhD, Bastiaan E. Schölzel, MD, PhD   +6 more
doaj   +1 more source

Stenosis of the Larynx [PDF]

The Boston Medical and Surgical Journal, 1909
n ...
openaire   +2 more sources

Deferral vs. performance of percutaneous coronary intervention of functionally non-significant coronary stenosis: 15-year follow-up of the DEFER trial.

European Heart Journal, 2015
AIMS Stenting an angiographically intermediate but functionally non-significant stenosis is controversial. Nevertheless, it has been questioned if deferral of a functionally non-significant lesion on the basis of fractional flow reserve (FFR) measurement,
F. Zimmermann, A. Ferrara, N. Johnson, L. X. V. Nunen, J. Escaned, Per Albertsson, R. Erbel, V. Legrand, H. Gwon   +8 more
semanticscholar   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

Advanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua, Marianna Barbuto, Matteo Calligaris, Roberto Di Gesù, Duilio Pagano, Rosalia Busà, Salvatore Gruttadauria, Simone Dario Scilabra, Antonio D'Amore, Maria Giovanna Francipane   +9 more
wiley   +1 more source