Results 81 to 90 of about 5,999,373 (245)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

“What Is a Step?” Differences in How a Step Is Detected among Three Popular Activity Monitors That Have Impacted Physical Activity Research

open access: yesSensors, 2018
(1) Background: This study compared manually-counted treadmill walking steps from the hip-worn DigiwalkerSW200 and OmronHJ720ITC, and hip and wrist-worn ActiGraph GT3X+ and GT9X; determined brand-specific acceleration amplitude (g) and/or frequency (Hz ...
Dinesh John   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Step-by-Step: Efficient Ship Detection in Large-Scale Remote Sensing Images

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
In the field of object detection in large-scale remote sensing images, achieving a good tradeoff between model accuracy and speed has been a long-standing challenge.
Wei Cao   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Internationalization of higher education institutions in Northern Europe in the light of Bologna - National and Institutional Case Studies [PDF]

open access: yes, 2004
This study is the basis for a summary report concerning the internationalization of higher education in the Nordic countries (see NIFU STEP report 8/2004)
Nokkala, Terhi   +2 more
core  

Single-Step FRET-Based Detection of Femtomoles DNA

open access: yesSensors, 2019
Sensitive detection of nucleic acids and identification of single nucleotide polymorphism (SNP) is crucial in diagnosis of genetic diseases. Many strategies have been developed for detection and analysis of DNA, including fluorescence, electrical ...
Kumar Sapkota   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Konturer av et Innlandsuniversitet: Vurdering av organisasjons-, styrings- og ledelsesmodeller [PDF]

open access: yes, 2009
NIFU STEP og Rokkansenteret fikk våren 2009 i oppdrag å utrede fremtidige modeller for hvordan et Innlandsuniversitet skal organiseres, styres og ...
Hope, Kristin   +3 more
core  

Utvalgsseleksjon og manglende data. Noen metodemessige utfordringer [PDF]

open access: yes, 2006
Arbeidsnotatet diskuterer noen metodemessige utfordringer ved håndtering av utvalgsseleksjon og manglende data, spesielt hvordan James Heckman's seleksjonsmodell kan anvendes for dette formålet.
Strøm, Bjarne
core   +2 more sources

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