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A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni +13 more
wiley +1 more source
From Waste to Value: Conversion of Calcium Sulfate to Vaterite via Carbon Capture and Storage
This study introduces a new concept for carbon management that relies on the carbonation of industrial gypsum waste and yields phase‐pure vaterite at ambient conditions without any additives. The obtained vaterite is further shown to be a reactive material that develops compressive strength in aqueous suspensions like conventional cements.
Carlos Pimentel +4 more
wiley +1 more source
Melt Grafting of Geometry‐Tailored Voltage Stabilizers for High‐Performance Polypropylene Insulation
A scalable one‐step melt grafting strategy is developed to enhance the dielectric properties of isotactic polypropylene by covalently incorporating thermally stable aromatic voltage stabilizers. This solvent‐free approach improves volume resistivity and DC breakdown strength through deep trap formation and charge localization, offering a sustainable ...
Nazirul Mubin bin Normansah +9 more
wiley +1 more source
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Stepped Wedge Cluster Randomized Trials: A Methodological Overview
World Neurosurgery, 2022Stepped wedge cluster randomized trials enable rigorous evaluations of health intervention programs in pragmatic settings. In the present study, we aimed to update neurosurgeon scientists on the design of stepped wedge randomized trials.We have presented an overview of recent methodological developments for stepped wedge designs and included an update ...
Fan Li, Rui Wang
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Power analysis for stepped wedge trials with multiple interventions
Statistics in Medicine, 2022Stepped wedge design (SWD) trials are cluster randomized trials that feature staggered, unidirectional cross‐over between treatment conditions. Existing literature on power for SWDs focuses primarily on designs with two conditions, typically a control and an intervention condition. However, SWDs with more than one treatment condition are being proposed
Phillip Sundin, Catherine M. Crespi
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Variance formulae for multiphase stepped wedge cluster randomized trial
Statistics in Medicine, 2020AbstractIn a multiphase stepped wedge cluster randomized trial (MSW‐CRT), more than one intervention will be initiated on each sequence in a fixed order. Hence, with the MSW‐CRT design, the effect of the first intervention can be evaluated when compared to control, as well as the added‐on effects of the subsequent interventions.
Pengyue Zhang +3 more
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Design and analysis of stepped wedge cluster randomized trials
Contemporary Clinical Trials, 2007Cluster randomized trials (CRT) are often used to evaluate therapies or interventions in situations where individual randomization is not possible or not desirable for logistic, financial or ethical reasons. While a significant and rapidly growing body of literature exists on CRTs utilizing a "parallel" design (i.e.
Michael A, Hussey, James P, Hughes
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Information Content of Cluster–Period Cells in Stepped Wedge Trials
Biometrics, 2018Summary Stepped wedge and other multiple-period cluster randomized trials, which collect data from multiple clusters across multiple time periods, are being conducted with increasing frequency; statistical research into these designs has not kept apace.
Jessica Kasza, Andrew B. Forbes
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Analysis of Data from a Stepped Wedge Trial
2021In this chapter the different methods for the analysis of data from a stepped wedge trial are discussed. These methods contain the comparison of different arms, the comparison of groups with a different number of intervention measurement, and the comparison of transitions.
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TVZ - Verpleegkunde in praktijk en wetenschap, 2021
Janneke de Man-Van Ginkel, Roelof Ettema
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Janneke de Man-Van Ginkel, Roelof Ettema
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