The effect of a postpartum IUD intervention on counseling and choice: Evidence from a cluster-randomized stepped-wedge trial in Sri Lanka [PDF]
, 2019 BACKGROUND: The International Federation of Gynaecology and Obstetrics (FIGO), in collaboration with the Sri Lankan College of Obstetrics and Gynaecologists (SLCOG), launched an initiative in 2014 to institutionalize immediate postpartum IUD (PPIUD ...
Canning, David +8 more
core +1 more source
Pilot and Feasibility Studies, 2018 Background Multimorbidity, polypharmacy, and older age predispose seniors to adverse drug events (ADE). Seniors with an ADE experience greater morbidity, mortality, and health care utilization compared to their younger counterparts.
Joanne Man-Wai Ho +9 more
doaj +1 more source
BMJ Open, 2021 Objectives Point-of-care ultrasound-guided regional anaesthesia (POCUS-GRA) provides safe, rapid analgesia for older people with hip fractures but is rarely performed in the emergency department (ED).
Debra Eagles +18 more
doaj +1 more source
阶梯整群随机试验 Stepped Wedge Cluster Randomized Trials
Zhongguo cuzhong zazhi, 2023 阶梯整群随机试验（stepped wedge cluster randomized trial，SW-CRT）是一种新型的研究设计，通常用于评价整群的服务或政策干预效果。该设计不需要单独设立对照，在设计初始阶段，所有整群均不暴露于干预，随后每一个观察期随机一组整群接受干预，进入干预组，直到所有整群均接受干预。本文从SW-CRT的基本原理、类别、研究设计、样本量计算、统计学方法和报告规范等方面进行介绍，为开展SW-CRT研究提供参考。 Abstract: The stepped wedge ...
王孟, 王春娟, 李子孝, 谷鸿秋
doaj +1 more source
The prevention and reduction of weight loss in an acute tertiary care setting: Protocol for a pragmatic stepped wedge randomised cluster trial (the PRoWL Project) [PDF]
, 2013 Background: Malnutrition, with accompanying weight loss, is an unnecessary risk in hospitalised persons and often remains poorly recognised and managed.
A Dickinson +85 more
core +3 more sources
Randomization-Based Confidence Intervals for Cluster Randomized Trials [PDF]
, 2020 In a cluster randomized trial (CRT), groups of people are randomly assigned to different interventions. Existing parametric and semiparametric methods for CRTs rely on distributional assumptions or a large number of clusters to maintain nominal ...
Rabideau, Dustin J, Wang, Rui
core +2 more sources
Trials, 2023 We previously described the hypotheses, outcomes, design, and analysis for E2C2, a pragmatic stepped-wedge trial to assess an intervention to improve symptom control in patients with cancer.
Jeph Herrin +4 more
doaj +1 more source
Developing and evaluating a lay health worker delivered implementation intervention to decrease engagement disparities in behavioural parent training: a mixed methods study protocol. [PDF]
, 2019 IntroductionBehavioural parent training (BPT) programmes are effective in preventing and treating early-onset conduct problems and child maltreatment. Unfortunately, pervasive mental health service disparities continue to limit access to and engagement ...
Barnett, Miya +5 more
core +1 more source
Stepped-wedge cluster randomised trials: where, when and why? [PDF]
Trials, 2015 The stepped wedge (SW) cluster randomised trial (CRT) design is being utilised at increasing pace. However, little is known about the standard of reporting of such trials, or how useful the design has proven to be in hindsight. Moreover, much debate exists around when the design should be preferred to the more classical parallel group (PG) CRT.
Grayling, Michael +2 more
openaire +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source