Results 121 to 130 of about 3,442,220 (258)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Williamsburg County First Steps Partnership fiscal year 2009 annual report [PDF]

open access: yes, 2009
This annual report from South Carolina First Steps provides statistics on school readiness and early education and explains results of First Steps programs in health, early education, families, child care, accountability, and partnerships.
South Carolina First Steps to School Readiness (Program)
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Research progress on sensitivity index of quality of specialist care

open access: yesHuli yanjiu, 2019
It summarized the definition,characteristics,formulation model,methods and steps of nursing quality sensitivity index and reviewed the nursing sensitive quality indicators in the specialist areas of emergency,intensive care unit(ICU), obstetrics ...
赵诗雨, 喻姣花
doaj  

Kershaw County First Steps Partnership fiscal year 2008 annual report [PDF]

open access: yes, 2008
This annual report from South Carolina First Steps provides statistics on school readiness and early education and explains results of First Steps programs in health, early education, families, child care, accountability, and partnerships.
South Carolina First Steps to School Readiness (Program)
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Horry County First Steps Partnership fiscal year 2008 annual report [PDF]

open access: yes, 2008
This annual report from South Carolina First Steps provides statistics on school readiness and early education and explains results of First Steps programs in health, early education, families, child care, accountability, and partnerships.
South Carolina First Steps to School Readiness (Program)
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Tender Steps

open access: yes
*Tender Steps is an artistic response to the grief and healing surrounding baby loss. Shot in a single, uninterrupted take, the film captures the raw emotions of a lived experience, set against the backdrop of Oker Tree in South Darley, Derbyshire. *
Marshall, A.
core  

Tender Steps - Festivity Tour 2025 [PDF]

open access: yes
Festivity is a free vibrant family-friendly countywide tour celebrating the incredible talents of Derbyshire’s musicians, poets, dancers, visual artists, crafts and storytellers. Arts Derbyshire has teamed up with the Tent People to create a magical mini-
Marshall, A.
core  

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