Results 121 to 130 of about 4,595,489 (342)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Variation of English business e-mails in Asian countries [PDF]
Ibérica, 2013 The overall aim of this paper is to detect whether there is language variation in a setting such as international business communication, in which interaction is expected to be precise and concise.
María Luisa Carrió-Pastor +1 more
doaj
10,000 Steps Workplaces Evaluation
, 2009 This report details the results of an evaluation of the 10,000 Steps programs and resources within workplaces. It examines the type of workplaces that utilise the program, how it has been used and the usefulness of the 10,000 Steps resources for ...
Duncan, Mitch J. +5 more
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Steps to get an Oregon driver's license. Tongan
, 2021 Video explaining steps to get an Oregon driver's license.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
First Steps: briefing document for schools [PDF]
, 2012 The Extending Learning Opportunities document is an update of the Study Support Code of Practice and is recommended for use by all schools, centres and organisations who deliver study support activities for children and young people.
Moore, Joanne, Vardy, S.
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Steps to get an Oregon driver's license. Vietnamese
, 2021 Video explaining steps to get an Oregon driver's license.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Decrease in weekend number of steps in adolescents
Acta Universitatis Palackianae Olomucensis. Gymnica, 2013 BACKGROUND: The activities with which young people spend the weekends do not support the prevalence of an active and healthy lifestyle enough. There are research evidence-based results that physical activity performed during weekend days is lower than ...
Jana Vašíčková +3 more
doaj