Results 131 to 140 of about 4,595,489 (342)
Steps for Conducting a Scoping Review.
Susanne Mak, A. Thomas
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Key time steps selection is essential for effective and efficient scientific visualization of large-scale time-varying datasets. We present a novel approach that can decide the number of most representative time steps while selecting them to minimize the
Zhou, Bo, Chiang, Yi-Jen
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
BACKGROUND: When it comes to physical activity, adolescents are the group at the highest risk. When monitoring physical activity in adolescents, it is necessary to differentiate school and weekend days.
Viera Bebčáková +4 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Genre Analysis of introduction section of English and Persian Articles in Mechanics [PDF]
This study was an attempt to conduct a contrastive study of genre analysis on the introduction section of English and Persian Mechanical Engineering Research Articles published in journals, following Swales' (1990) CARS (Creating a Research Space) model.
Atefeh Mobasher
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
<h2>New Features</h2> <ol> <li>Introduce a new solver named <code>TetVesicle</code> that simulates vesicles, lipid rafts and related phenomena such as endocytosis, exocytosis and active transport on virtual actin ...
Hepburn, Iain +2 more
core +1 more source

