Results 171 to 180 of about 13,728 (257)
Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis
This review highlights synthetic advances (2013–2025) in intramolecular C─N bond formation for constructing the pharmaceutically relevant pyrrolidine core. The review is organized into five methodological clusters: 1) intramolecular alkene/alkyne amination; 2) tandem annulations, which involve C─N bond formation as the key step; 3) nucleophilic ...
Rasma Kroņkalne, Māris Turks
wiley +1 more source
Unraveling enantioselective metabolism: Human cytochrome P450s in arachidonic acid biotransformation. [PDF]
Isse FA, El-Sherbeni AA, El-Kadi AOS.
europepmc +1 more source
Phytochemicals in Asthma Management: Mechanism, Translational Gap and Clinical Integration
The phytochemicals including flavonoids, alkaloids, terpenoids, and saponins modulate inflammatory, oxidative, and immune pathways in asthma. It highlights their mechanisms of action, translational challenges, advanced formulation strategies, and emerging clinical potential as adjunct therapies for precision‐based asthma management.
Pulak Majumder, Trisita Majumder
wiley +1 more source
The End of the Beginning of Mechanical Stereochemistry. [PDF]
Goldup SM.
europepmc +1 more source
This research introduces an ortho‐palladated oxazolone moiety that can undergo rapid and reversible photocycloaddition by low‐intensity green light irradiation. Integration of such a photoresponsive function into crosslinked polymer structures enables rapid photo‐ and thermo‐switching of polymer properties, presenting a unique light‐directed covalent ...
Wai Lean Koay +7 more
wiley +1 more source
Single-crystal X-ray diffraction analysis and mechanistic implications of (2R*,3R*)-2-(2-phenoxyethyl)tetrahydrofuran-3-yl acetate. [PDF]
Kelley SP, Nirpal AK, Sathyamoorthi S.
europepmc +1 more source
Kineochelins—A New Group of Siderophores From an Antarctic Bacterium
Genome‐guided analysis of an Antarctic Actinokineospora strain led to the discovery of kineochelins, a new group of siderophores involved in iron sequestration and microbial competition. Kineochelin production inhibits co‐occurring bacteria and clinically relevant yeasts, highlighting Antarctic microorganisms as promising sources of bioactive natural ...
Stanislava Kralova +12 more
wiley +1 more source
Oxidation-Induced Scaffold Remodeling in <i>Ainsliaea</i> Disesquiterpenoids: Total Synthesis of Macrocephadiolide A. [PDF]
Gennaiou K, Zografos AL.
europepmc +1 more source
Drivers of strigolactone diversity: P450s in strigolactone biosynthesis
This review summarizes the discovery and functional identification of cytochrome P450 in strigolactone biosynthesis, classifies and summarizes the members discovered so far, clarifies their biological significance, discusses the technology of strigolactone synthesis research, and finally describes some problems in strigolactone research and potential ...
Changbin Niu +2 more
wiley +1 more source

