Results 51 to 60 of about 21,877 (199)

Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects [PDF]

open access: yes, 2009
Many neurodegenerative diseases exhibit axonal pathology, transport defects, and aberrant phosphorylation and aggregation of the microtubule binding protein tau. While mutant tau protein in frontotemporal dementia and parkinsonism linked to chromosome 17
Falzone, Tomas Luis   +6 more
core   +1 more source

Diagnostic Value of Glycocalyx Shedding in Blood for Differentiating between Parkinson's Disease and Multiple System Atrophy

open access: yesMovement Disorders, EarlyView.
Abstract Background Blood–brain barrier disruption is increasingly recognized in synucleinopathies, but the role of the endothelial glycocalyx (GLX) in Parkinson's disease (PD) and multiple system atrophy (MSA) remains unclear. Objectives The aim was to determine whether plasma GLX markers differ between PD, MSA, and healthy controls (HC), relate to ...
Jonas Folke   +15 more
wiley   +1 more source

POLISH STEREOLOGY – A HISTORICAL REVIEW

open access: yesImage Analysis and Stereology, 2017
In the paper, the authors present the history of stereology development in Poland from the 1930s until now. The authors concentrate on the talented scholars whose hard work, dedication, and enthusiasm contributed to popularizing stereological methods of ...
Aneta Gądek-Moszczak, Piotr Matusiewicz
doaj   +1 more source

On the capacity functional of excursion sets of Gaussian random fields on $\R^2$ [PDF]

open access: yes, 2014
When a random field $(X_t, \ t\in {\mathbb R}^2)$ is thresholded on a given level $u$, the excursion set is given by its indicator $~1_{[u, \infty)}(X_t)$.
Kratz, Marie, Nagel, Werner
core   +3 more sources

Influence of Heat Treatment Temperature on Crevice and Pitting Corrosion of UNS S32205 Duplex Stainless Steel

open access: yessteel research international, EarlyView.
Heat treatments that alter the proportions of austenite and ferrite phases or induce the precipitation of phases such as sigma in duplex stainless steel UNS S32205 make it more susceptible to pitting and crevice corrosion. However, the effects of these treatments are not always evident when analyzed using the cyclic polarization technique.
Alba Regina Turin   +8 more
wiley   +1 more source

Multiple Periapical Lesions Influence the Expression of TLR4/NF‐κB Pathway Components and the Development of Hepatic Injuries in Healthy and Chronic Alcohol‐Consuming Rats

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim To evaluate the impact of multiple apical periodontitis (AP) on the expression of TLR4/NF‐κB pathway components, proinflammatory cytokine levels, and development of hepatic injuries in rats with and without chronic alcohol consumption. Methodology Thirty‐two rats were assigned to four groups (n = 8): Control, AP, Alcohol, and Alcohol+AP ...
Karem Paula Pinto   +6 more
wiley   +1 more source

Macroscopical and histological characterization of the perineal membrane and deep perineal pouch

open access: yesJournal of Anatomy, EarlyView.
The existence of the deep transverse perineal muscle remains controversial. While the macroscopic appearance of the tissue in the deep perineal pouch differs between men and women, the differences in the histological composition of this fibromuscular plate is still unclear.
Morten Kampelmann   +3 more
wiley   +1 more source

High‐elevation adaptation and gestational hypoxia jointly shape vascular development in a rodent placenta

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Kathryn Wilsterman   +6 more
wiley   +1 more source

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae   +53 more
wiley   +1 more source

Intestinal responses in pacu (Piaractus mesopotamicus) exposed to fasting and refeeding nutritional management

open access: yesThe Anatomical Record, Volume 309, Issue 3, Page 663-673, March 2026.
Abstract Fasting is a practice in the aquaculture industry that aims to reduce feed costs. This practice can affect the gastrointestinal system of fish. The intestine plays a pivotal role in the nutrition and overall health of fishes. The present study sought to evaluate the effects of fasting and refeeding on body weight, intestine somatic index (ISI),
Karine Nathiele Nogueira Farias   +7 more
wiley   +1 more source

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