Macroscopical and histological characterization of the perineal membrane and deep perineal pouch
The existence of the deep transverse perineal muscle remains controversial. While the macroscopic appearance of the tissue in the deep perineal pouch differs between men and women, the differences in the histological composition of this fibromuscular plate is still unclear.
Morten Kampelmann +3 more
wiley +1 more source
Association of intracellular and synaptic organization in cochlear inner hair cells revealed by 3D electron microscopy [PDF]
The ways in which cell architecture is modelled to meet cell function is a poorly understood facet of cell biology. To address this question, we have studied the cytoarchitecture of a cell with highly specialised organisation, the cochlear inner hair ...
Billups +35 more
core +2 more sources
Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses
Abstract Uteroplacental insufficiency impairs kidney development and programs male‐onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting that the lifestyle of growth‐restricted females can have further influence on F2 kidney ...
Jessica F. Briffa +11 more
wiley +1 more source
Nano-structured materials attract a growing attention due to their superior mechanical and physical properties. Such properties are inherently related to the unique structure which is controlled at the nano-scale. In the early stage of their development,
Tomasz Wejrzanowski +2 more
doaj +1 more source
Partial and Interaction Spline Models for the Semiparametric Estimation of Functions of Several Variables [PDF]
A partial spline model is a model for a response as a function of several variables, which is the sum of a smooth function of several variables and a parametric function of the same plus possibly some other variables.
Wahba, Grace
core +1 more source
Cauchy's formulas for random walks in bounded domains
Cauchy's formula was originally established for random straight paths crossing a body $B \subset \mathbb{R}^{n}$ and basically relates the average chord length through $B$ to the ratio between the volume and the surface of the body itself.
Alain Mazzolo +9 more
core +3 more sources
Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Kathryn Wilsterman +6 more
wiley +1 more source
Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels [PDF]
There is evidence that chronic ethanol treatment (CET) disrupts the biological rhythms of various brain functions and behaviors. Because the suprachiasmatic nucleus (SCN) is widely recognized as the dominant pacemaker of the circadian system, we have ...
Almeida, OFX +5 more
core +1 more source
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen +17 more
wiley +1 more source
Quantitative morphology of renal cortical structures during compensatory hypertrophy [PDF]
The compensatory hypertrophy in different renal cortical structures was studied in rats 10 and 21 days after unilateral nephrectomy (UNX). Quantitative morphological/stereological analysis revealed significant increases in total renal cortical volume ...
Beck, Franz-X. +4 more
core +1 more source

