Results 61 to 70 of about 21,877 (199)

Tyrosine Hydroxylase Deficiency Impairs TH Axonal Transport, Brain Function, and Neuronal Plasticity

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Tyrosine hydroxylase deficiency (THD) is a rare genetic disorder caused by biallelic pathogenic variants in the Th gene, leading to a deficiency in the rate‐limiting enzyme for the synthesis of dopamine (DA) and other catecholamine neurotransmitters.
Tie‐Jun Sten Shi, Kunwar Jung‐KC, Gong‐Wei Lyu, Liang Han, Ming Ying, Beat Thöny, Aurora Martinez   +6 more
wiley   +1 more source

Rapid, learning-induced inhibitory synaptogenesis in murine barrel field [PDF]

, 2010
The structure of neurons changes during development and in response to injury or alteration in sensory experience. Changes occur in the number, shape, and dimensions of dendritic spines together with their synapses. However, precise data on these changes
Cybulska-Klosowicz, A, Furness, DN, Glazewski, S, Jasinska, M, Kossut, M, Pyza, E, Siucinska, E   +6 more
core   +1 more source

Basic Stereology [PDF]

Microscopy Today, 2003
Abstract Many us who use microscopes are interested in the internal structure or components of three-dimensional objects. Often we must section these objects to observe these internal components. For many years, microtomes have been used to make physical sections, but in recent years confocal microscopes, MR imaging, CT scanners, and ...
openaire   +1 more source

Biochemical, morphological and molecular assessments of n butanol fraction of Phoenix dactylifera L. following exposure to inorganic mercury on the liver of Wistar rats

Laboratory Animal Research
Background Mercury chloride (HgCl2) damages tissues it comes in contact with in sufficient concentration. This study evaluated the protective effects of n-butanol fraction of Phoenix dactylifera (BFPD) on mercury-triggered liver toxicity in Wistar rats ...
Musa Garba Abubakar, AN Agbon, SA Musa, WO Hamman, SB Oladele   +4 more
doaj   +1 more source

Association of intracellular and synaptic organization in cochlear inner hair cells revealed by 3D electron microscopy [PDF]

, 2015
The ways in which cell architecture is modelled to meet cell function is a poorly understood facet of cell biology. To address this question, we have studied the cytoarchitecture of a cell with highly specialised organisation, the cochlear inner hair ...
Billups, Bullen, Csordas, Deerinck, Denk, Duncker, Esterberg, Francis, Harlow, Heidrych, Kantardzhieva, Khimich, Kujawa, Lenzi, Liberman, Liberman, Martínez-Menárguez, Mastronarde, Mastronarde, Matthews, Neef, Nouvian, Peng, Rowland, Safieddine, Schneider, Snellman, Spicer, Spicer, Steyger, Szule, Takumi, Tuffy, Vogl, Yin, Zelena   +35 more
core   +2 more sources

Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses

Experimental Physiology, Volume 111, Issue 3, Page 1365-1386, 1 March 2026.
Abstract Uteroplacental insufficiency impairs kidney development and programs male‐onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting that the lifestyle of growth‐restricted females can have further influence on F2 kidney ...
Jessica F. Briffa, Sogand Gravina, Viktoria F. Richter, Dayana Mahizir, Kristina Anevska, Yeukai T. M. Mangwiro, James S. M. Cuffe, Fadi Charchar, Glenn D. Wadley, Deanne H. Hryciw, Karen M. Moritz, Mary E. Wlodek   +11 more
wiley   +1 more source

Jean-Louis Chermant (June 24, 1941 – August 11, 2024)

Image Analysis and Stereology
Jean-Louis Chermant was widely known within the scientific community focused on image analysis and stereology, especially in materials science applications.
Leszek Wojnar
doaj   +1 more source

Epigenetic modulation of AREL1 and increased HLA expression in brains of multiple system atrophy patients

Acta Neuropathologica Communications, 2020
Multiple system atrophy (MSA) is a rare disease with a fatal outcome. To date, little is known about the molecular processes underlying disease development.
Rasmus Rydbirk, Jonas Folke, Florence Busato, Elodie Roché, Alisha Shahzad Chauhan, Annemette Løkkegaard, Anne-Mette Hejl, Matthias Bode, Morten Blaabjerg, Mette Møller, Erik Hvid Danielsen, Tomasz Brudek, Bente Pakkenberg, Jorg Tost, Susana Aznar   +14 more
doaj   +1 more source

Cyclic GMP in the pig vitreous and retina after experimental retinal detachment [PDF]

, 2008
Purpose: Earlier studies have revealed a decreased level of cGMP in vitreous fluid obtained from patients with a retinal detachment. To further investigate this phenomenon, we developed an experimental retinal detachment model in pigs.
Diederen, R., Heij, E.C., La, Lemmens, M.A.M., Kijlstra, A., Vente, J., De, Hendrikse, F.   +5 more
core  

Small is the New Large: Demonstration of how Microanalyses Elucidate Large‐Scale CO2 Uptake Through Mineralization

Advanced Sustainable Systems, Volume 10, Issue 2, February 2026.
Imaging techniques like X‐ray microcomputed tomography and electron microscopy are integrated to understand the CO2 mineralization process at the pore‐scale. These techniques are used to characterise the reaction progression in basalt. They increase the reliability of reactive transport modeling and consequently improve the CO2 storage capacity ...
Faisal W. K. Khudhur, Ian B. Butler, Stuart M. V. Gilfillan   +2 more
wiley   +1 more source