Results 61 to 70 of about 22,135 (213)

Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ex vivo brain slice preparation is a popular technique in neuroscience research with many variations in preparation method. We compared two popular variations in brain slice preparation and found that the choice of brain slice preparation technique significantly affects the viability of neuronal preparation.
Felix Chan, Anupam Hazra, Ashan Jayasekera, Katherine Huang, Shuna Whyte, Leolie Telford‐Cooke, Kamilah Lakhani, Xiaomeng Li, Rebecca Shields, Angeline Kosim, Darwin Su, Carol Murray, Mark O. Cunningham   +12 more
wiley   +1 more source

Brain Volume Estimation Enhancement by Morphological Image Processing Tools

Journal of Biomedical Physics and Engineering, 2017
Background: Volume estimation of brain is important for many neurological applications. It is necessary in measuring brain growth and changes in brain in normal/ abnormal patients. Thus, accurate brain volume measurement is very important.
Zeinali R., Keshtkar A., Zamani, A., Gharehaghaji, N.   +3 more
doaj  

Jean-Louis Chermant (June 24, 1941 – August 11, 2024)

Image Analysis and Stereology
Jean-Louis Chermant was widely known within the scientific community focused on image analysis and stereology, especially in materials science applications.
Leszek Wojnar
doaj   +1 more source

Comparison of methods for quantifying primordial follicles in the mouse ovary

Journal of Ovarian Research, 2020
Background Accurate evaluation of primordial follicle numbers in mouse ovaries is an essential endpoint for studies investigating how endogenous and exogenous insults, such as maternal aging and chemotherapy, impact the ovarian reserve. In this study, we
Urooza C. Sarma, Amy L. Winship, Karla J. Hutt   +2 more
doaj   +1 more source

Basic Stereology [PDF]

Microscopy Today, 2003
Abstract Many us who use microscopes are interested in the internal structure or components of three-dimensional objects. Often we must section these objects to observe these internal components. For many years, microtomes have been used to make physical sections, but in recent years confocal microscopes, MR imaging, CT scanners, and ...
openaire   +1 more source

Robot‐Assisted Automated Serial‐Sectioning and Imaging for 3D Microstructural Investigations

Advanced Engineering Materials, Volume 28, Issue 2, January 21, 2026.
A fully automated 3D microstructure characterization platform provides new insights into materials. This robot‐assisted system performs serial‐sectioning, etching, and optical imaging to generate large‐volume 3D reconstructions with submicron resolution.
Michael Moschetti, Anton Lemiasheuski, Evgenia Bajer, Ilja Porohovoj, Artur Göbel, Anja Pfennig, Dirk Bettge, Robert Maaß   +7 more
wiley   +1 more source

Biochemical, morphological and molecular assessments of n butanol fraction of Phoenix dactylifera L. following exposure to inorganic mercury on the liver of Wistar rats

Laboratory Animal Research
Background Mercury chloride (HgCl2) damages tissues it comes in contact with in sufficient concentration. This study evaluated the protective effects of n-butanol fraction of Phoenix dactylifera (BFPD) on mercury-triggered liver toxicity in Wistar rats ...
Musa Garba Abubakar, AN Agbon, SA Musa, WO Hamman, SB Oladele   +4 more
doaj   +1 more source

In vivo evidence for NMDA receptor mediated excitotoxicity in a murine genetic model of Huntington Disease [PDF]

, 2008
N-methyl-D-aspartate receptor (NMDAR) mediated excitotoxicity is implicated as a proximate cause of neurodegeneration in Huntington Disease (HD). However, this hypothesis has not been tested rigorously in vivo. NMDAR NR2B-subunits are the predominant NR2
Joe Tsien, Mary Heng, Peter Detloff, Phillip Wang, Roger Albin   +4 more
core   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Generative Adversarial Framework to Calibrate Excursion Set Models for the 3D Morphology of All‐Solid‐State Battery Cathodes

Advanced Intelligent Systems, Volume 8, Issue 1, January 2026.
Worklow for calibrating excursion sets of random fields using methods from generative artificial intelligence. This article presents a computational method for generating virtual 3D morphologies of functional materials using low‐parametric stochastic geometry models, that is, digital twins, calibrated with 2D microscopy images.
Orkun Furat, Sabrina Weber, Anina Dufter, Johannes Schubert, René Rekers, Maximilian Luczak, Erik Glatt, Andreas Wiegmann, Jürgen Janek, Anja Bielefeld, Volker Schmidt   +10 more
wiley   +1 more source