Metabolic changes during cardiac regeneration in the axolotl
Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich +10 more
wiley +1 more source
Is a Team-based Learning Approach to Anatomy Teaching Superior to Didactic Lecturing?
Objectives: Team-based learning (TBL) is used in the medical field to implement interactive learning in small groups. The learning of anatomy and its subsequent application requires the students to recall a great deal of factual content. The aims of this
Naghme Ghorbani +2 more
doaj
Multiple system atrophy (MSA) is a rare disease with a fatal outcome. To date, little is known about the molecular processes underlying disease development.
Rasmus Rydbirk +14 more
doaj +1 more source
Focus on orexinergic neurons: omics study reveals glial changes and neuroinflammation in the lateral hypothalamic area as key factors driving the initial vulnerability in Alzheimer's disease [PDF]
Abstract Background The neuromodulatory subcortical system (NSS) is vital for homeostatic balance and is among the earliest regions to accumulate tau pathology in Alzheimer's disease (AD), undergoing marked degeneration by late‐stage AD. Within the NSS, orexinergic neurons (OrxN) regulate wakefulness, appetite, and sleep‐wake transitions.
Satpati A +16 more
europepmc +2 more sources
This protocol is used to quantify the number of TH+ cells in the substantia nigra pars compacta.
openaire +1 more source
Pioglitazone Ameliorates Neuron Loss in the Cortex after Aluminum-Treatment in Rats
The objective was evaluation of the effects of pioglitazone on medial prefrontal cortex (mPFC) of the rats exposed to aluminum (Al). Al induces structural changes in several brain regions, including mPFC.
Ali Rafati +2 more
doaj +1 more source
Analysis of Vesicular Basalts and Lava Emplacement Processes for Application as a Paleobarometer/Paleoaltimeter [PDF]
We have developed a method for determining paleoelevations of highland areas on the basis of the vesicularity of lava flows. Vesicular lavas preserve a record of paleopressure at the time and place of emplacement because the difference in internal ...
Carlson, William D. +2 more
core +2 more sources
Ethane-beta-Sultam Modifies the Activation of the Innate Immune System Induced by Intermittent Ethanol Administration in Female Adolescent Rats [PDF]
Intermittent ethanol abuse or ‘binge drinking’ during adolescence induces neuronal damage, which may be associated with cognitive dysfunction. To investigate the neurochemical processes involved, rats were administered either 1 g/kg or 2 g/kg ethanol in ...
Colivicchi, M.A. +10 more
core +1 more source
The present study was carried out to investigate the effects of Rudgea viburnoides infusion on the body biometry and testicular morphometry and stereology of adult Wistar rats.
Juliana Castro Monteiro +3 more
doaj +1 more source
Strategies for maximizing ATP supply in the microsporidian Encephalitozoon cuniculi: direct binding of mitochondria to the parasitophorous vacuole and clustering of the mitochondrial porin VDAC [PDF]
Microsporidia are obligate intracellular parasites with extremely reduced genomes and a dependence on host-derived ATP. The microsporidium Encephalitozoon cuniculi proliferates within a membranous vacuole and we investigated how the ATP supply is ...
Bhella, David +3 more
core +2 more sources

