Results 61 to 70 of about 242,918 (218)

Current status of stereotactic body radiotherapy for the treatment of hepatocellular carcinoma [PDF]

Yeungnam University Journal of Medicine, 2019
Stereotactic body radiotherapy (SBRT) is an advanced form of radiotherapy (RT) with a growing interest on its application in the treatment of hepatocellular carcinoma (HCC).
Jongmoo Park, Jae Won Park, Min Kyu Kang
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Technological quality requirements for stereotactic radiotherapy : Expert review group consensus from the DGMP Working Group for Physics and Technology in Stereotactic Radiotherapy. [PDF]

, 2020
This review details and discusses the technological quality requirements to ensure the desired quality for stereotactic radiotherapy using photon external beam radiotherapy as defined by the DEGRO Working Group Radiosurgery and Stereotactic Radiotherapy ...
Baus, Wolfgang W., Werner, Rene, Loutfi-Krauss, Britta, Fix, Michael K., Gauer, Tobias, Baus, Wolfgang W, Brunner, Thomas B, Manser, Peter, Fleckenstein, Jens, Schmitt, Daniela, Brunner, Thomas B., Moustakis, Christos, Blanck, Oliver, Wilhelm, Maria-Lisa   +13 more
core   +2 more sources

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Stereotactic ablative body radiotherapy (SAbR) for oligometastatic cancer [PDF]

The British Journal of Radiology, 2017
The metastatic state of most solid cancers traditionally has been regarded as an incurable dissemination of disease, with treatment focused on delaying progression rather than eliminating all tumour burden. In this setting, local therapies including surgery and radiotherapy are directed at quality of life end points and not at improvement in survival ...
Neil B, Desai, Aaron M, Laine, Robert D, Timmerman   +2 more
openaire   +2 more sources

Precision Oncology via Radiotherapy‐Triggered Drug Delivery: Mechanisms, Molecular Engineering, and Clinical Translation

Advanced Science, EarlyView.
This review redefines radiotherapy‐triggered drug delivery systems through structural disassembly and molecular actuation, proposing a translation‐oriented framework for dose‐correlated activation to advance clinically integrated precision oncology. ABSTRACT Radiotherapy‐triggered drug delivery systems (RDDS) promise to integrate the spatial precision ...
Jianv Jiang, Tanfeng Zhang, Junliang Dong, Wenjing Sun   +3 more
wiley   +1 more source

SABR for oligometastatic renal cell carcinoma

Clinical and Translational Radiation Oncology
Stereotactic ablative body radiotherapy (SABR) aims to accurately deliver a higher than conventional dose of radiotherapy to a well-defined target tumour incorporating advanced immobilisation and imaging techniques.
Chang David, Ali Muhammad, Udovicich Cristian, Tran Ben, Azad Arun, Au Lewis, Spain Lavinia, Perera Marlon, Siva Shankar   +8 more
doaj   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Brief Report on Radiological Changes following Stereotactic Ablative Radiotherapy (SABR) for Early-Stage Lung Tumors: A Pictorial Essay

, 2018
Distinctive patterns of early and late benign fibrosis are commonly observed after stereotactic ablative radiotherapy for lung malignancies. These changes on computed tomography scans need to be distinguished from so-called high-risk radiological ...
Senan, Suresh, Ronden, Merle I, Palma, David, David Palma, Merle I. Ronden, Suresh Senan, Slotman, Ben J, Ben J. Slotman   +7 more
core   +1 more source

Intrafraction motion and impact of margin reduction for MR‐Linac online adaptive radiotherapy for pancreatic cancer treatments

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 17-24, March 2025.
This analysis included quantification of intrafraction motion in pancreas stereotactic ablative radiotherapy treated on the MR‐Linac, leading to the development of adjusted (PTV) margins. Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior ...
Ashleigh Fasala, Madeline Carr, Yolanda Surjan, Parmoun Daghigh, Jeremy de Leon, Abbey Burns, Vikneswary Batumalai   +6 more
wiley   +1 more source