Results 71 to 80 of about 242,918 (218)

Stereotactic Radiotherapy in Uveal Melanoma

, 2014
Uveal melanoma is the most common primary malignant intraocular neoplasm in adults. The aims of treatment of the uveal melanoma are to prevent the metastatic spread of the disease and to preserve as much useful vision as possible.
Ela Delikgöz Soykut, Yıldız Yükselen Güney, Ayşen Dizman   +2 more
core   +1 more source

Radiobiology of stereotactic radiotherapy [PDF]

, 2022
This paper focuses on the radiobiological mechanisms underlying the effects of stereotactic radiotherapy (SRT) which, despite SRT expansion, have not yet been fully elucidated.
Becherini, Carlotta; Radiotherapy Unit, Oncology Department, Azienda Ospedaliera Universitaria Careggi, University of Florence, Italy, Mangoni, Monica; Radiotherapy Unit, Oncology Department, Azienda Ospedaliera Universitaria Careggi, University of Florence, Italy, Borghesi, Simona; Radiation Oncology Unit of Arezzo-Valdarno, Azienda USL Toscana Sud Est, Italy, Aristei, Cynthia; Radiation Oncology Section, University of Perugia and Perugia General Hospital, Italy, Perugia, Italy   +3 more
core   +1 more source

The role of stereotactic ablative radiotherapy in oncological and non-oncological clinical settings: Highlights from the 7th Meeting of AIRO - Young Members Working Group (AIRO Giovani) [PDF]

, 2014
Stereotactic ablative radiotherapy is a modern cancer treatment strategy able to deliver highly focused radiation in one or a few fractions with a radical intent in several clinical settings.
Tiziana Comito, Patrizia Ciammella, Bonomo, P., Stefano Vagge, Fiore, M, Fiore, M., Bruni, Alessio, Ciammella, Patrizia, Fiorentino, Alba, Comito, T, Pierluigi Bonomo, Amelio, D, Cecconi, A., Cecconi, Agnese, Greto, D, Filippo Alongi, Andrea Riccardo Filippi, De Bari, Berardino, Bonomo, Pierluigi, Pinzi, V, Fiorentino, A, Fiore, Michele, Chiesa, Silvia, Michele Fiore, Bonomo, P, Comito, T., Amelio, D., Greto, D., Alessio Bruni, Alongi, Filippo, Bruni, A, Bruni, A., Dante Amelio, Greto, Daniela, Vagge, S, Mortellaro, G, Chiesa, S, Agnese Cecconi, Chiesa, S., Pierfrancesco Franco, Filippi, A.R., Pinzi, Valentina, Trovo', M, Alongi, F, De Bari, B, Pinzi, V., Ciammella, P, Mortellaro, Gianluca, Filippi, Andrea Riccardo, Ciammella, P., Vagge, S., Trovò, M., Trovo, Marco, Mortellaro, G., Fiorentino, A., Comito, Tiziana, Franco, Pierfrancesco, Alongi, F., Gianluca Mortellaro, Amelio, Dante, Berardino De Bari, Silvia Chiesa, De Bari, B., Daniela Greto, Franco, P, Marco Trovo', Vagge, Stefano, Alba Fiorentino, Filippi, AR, Franco, P., Cecconi, A, Valentina Pinzi   +71 more
core   +2 more sources

SABR-BRIDGE: Stereotactic ABlative Radiotherapy Before Resection to AvoId Delay for Early-Stage LunG Cancer or OligomEts During the COVID-19 Pandemic

Frontiers in Oncology, 2020
Surgical resection is the standard-of-care approach for early-stage non-small cell lung cancer (NSCLC). Surgery is also considered an acceptable standard infit patients with oligometastatic lesions in the lungs. The COVID-19 pandemic has led to worldwide
Biniam Kidane, Biniam Kidane, Biniam Kidane, Jonathan Spicer, Jonathan Spicer, Julian O. Kim, Julian O. Kim, Pierre-Olivier Fiset, Bassam Abdulkarim, Richard Malthaner, Richard Malthaner, David Palma, David Palma   +12 more
doaj   +1 more source

Stereotactic Ablative Body Radiotherapy for the Treatment of Spinal Oligometastases [PDF]

Clinical Oncology, 2017
To report multicentre outcomes of patients with spinal oligometastases treated with stereotactic ablative body radiotherapy (SABR). The primary objective was to estimate the widespread failure-free survival (WFFS) at 2 years - defined as freedom from metastases not amenable to local salvage therapy and death.Patients with one to three metastases ...
J.H. Chang, S. Gandhidasan, R. Finnigan, D. Whalley, R. Nair, A. Herschtal, T. Eade, A. Kneebone, J. Ruben, M. Foote, S. Siva   +10 more
openaire   +4 more sources

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

Precision Radiation Oncology, EarlyView.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu, Yang Zhang, Zuomin Wang, Zongjuan Li, Shisuo Du   +4 more
wiley   +1 more source

The confluence of stereotactic ablative radiotherapy and tumor [PDF]

, 2011
Stereotactic radiation approaches are gaining more popularity for the treatment of intracranial as well as extracranial tumors in organs such as the liver and lung.
Robert Timmerman, Sarah E Hoffe, William H Mcbride, Steven Eric Finkelstein, Constantine A Mantz, Dörthe Schaue, George D Wilson   +6 more
core  

Synergistic effects and clinical utilization of radioimmunotherapy for brain metastases from driver mutation‐negative non‐small cell lung cancer

Precision Radiation Oncology, EarlyView.
This review summarizes how combining radiotherapy with immune checkpoint inhibitors overcomes the immunosuppressive brain microenvironment in non‐small cell lung cancer (NSCLC) brain metastases. The synergy enhances immune cell infiltration and systemic anti‐tumor activity, improving survival outcomes for patients.
Silai Yu, Jianjiao Ni, Hongru Chen, Nuan Weng, Xi Yang, Xiao Chu, Li Chu, Zhengfei Zhu   +7 more
wiley   +1 more source

A phase I dose-escalation trial of stereotactic ablative body radiotherapy for non-spine bone and lymph node metastases (DESTROY-trial)

Radiation Oncology, 2018
Background In an oligometastatic setting, metastasis-directed treatment could render patients disease free, possibly for a protracted interval. Stereotactic ablative radiotherapy (SABR) is one of the treatment modalities that can be offered to these ...
Carole Mercier, Piet Dirix, Paul Meijnders, Peter Vermeulen, Steven Van Laere, Hilde Debois, Philippe Huget, Dirk Verellen   +7 more
doaj   +1 more source

Oligometastatic breast cancer and metastasis-directed treatment: an aggressive multimodal approach to reach the cure

Therapeutic Advances in Medical Oncology, 2023
Metastatic breast cancer (BC) is considered an incurable disease and is usually treated with palliative intent. However, about 50% of metastatic BCs present with only a few metastatic lesions and are characterized by longer overall survival.
Filippo Merloni, Michela Palleschi, Chiara Casadei, Antonino Romeo, Annalisa Curcio, Roberto Casadei, Franco Stella, Giorgio Ercolani, Caterina Gianni, Marianna Sirico, Simona Cima, Samanta Sarti, Lorenzo Cecconetto, Giandomenico Di Menna, Ugo De Giorgi   +14 more
doaj   +1 more source