Results 31 to 40 of about 3,454,417 (246)

Definition and quality requirements for stereotactic radiotherapy: consensus statement from the DEGRO/DGMP Working Group Stereotactic Radiotherapy and Radiosurgery [PDF]

, 2020
Stereotactic radiotherapy with its forms of intracranial stereotactic radiosurgery (SRS), intracranial fractionated stereotacticradiotherapy (FSRT) and stereotactic body radiotherapy (SBRT) is today a guideline-recommended treatment for malignant or ...
Tanadini-Lang, Stephanie, Baus, Wolfgang W., Guckenberger, Matthias; https://orcid.org/, Gauer, Tobias, Baus, Wolfgang W, Combs, Stephanie E, Guckenberger, Matthias, Grosu, Anca L, Combs, Stephanie E., Engenhart-Cabillic, Rita, Debus, Jürgen, Tanadini-Lang, Stephanie; https://orcid.org/, Schmitt, Daniela, Moustakis, Christos, Blanck, Oliver, Grosu, Anca L.   +15 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Stereotactic body radiotherapy: a new paradigm in the management of spinal metastases. [PDF]

, 2013
Spine stereotactic body radiotherapy is based on delivering high biologically effective doses to spinal metastases, with the intent to maximize both tumor and pain control.
Letourneau, Daniel, Thibault, Isabelle, Perry, James, Sahgal, Arjun, Husain, Zain A, Suh, John, Chiang, Veronica, Ma, Lijun, Chang, Eric L, Keller, Harald, Rampersaud, Raja K, Larson, David A   +11 more
core   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

The use of stereotactic radiotherapy in the treatment of lung malignancies — a scoping review

Oncology in Clinical Practice
INTRODUCTION: Lung cancer remains as main cause of cancer-related mortality, despite new advances, with many patients remaining inoperable. Novel methods of radiotherapy, including stereotactic body radiotherapy (SBRT), can provide survival benefits in ...
Chara Chantzara, Eleni Tzanetou, Hatham El-Ghobashy, Sotiris Christoforou, Datis Kalali   +4 more
doaj   +1 more source

Management of Chordoma and Chondrosarcoma with Fractionated Stereotactic Radiotherapy

Frontiers in Surgery, 2017
ObjectiveTo evaluate the efficacy and toxicity of fractionated stereotactic radiotherapy (FSRT) for chordoma and chondrosarcoma.MethodsTwenty consecutive patients with a histopathologic diagnosis of chordoma (n = 16) or chondrosarcoma (n = 4) treated ...
Harish N. Vasudevan, Harish N. Vasudevan, David R. Raleigh, Julian Johnson, Adam A. Garsa, Philip V. Theodosopoulos, Manish K. Aghi, Christopher Ames, Michael W. McDermott, Igor J. Barani, Steve E. Braunstein   +10 more
doaj   +1 more source

Job stress and job satisfaction of physicians, radiographers, nurses and physicists working in radiotherapy : a multicenter analysis by the DEGRO Quality of Life Work Group [PDF]

, 2009
Background Ongoing changes in cancer care cause an increase in the complexity of cases which is characterized by modern treatment techniques and a higher demand for patient information about the underlying disease and therapeutic options.
Sehlen Susanne, Bölling Tobias, Dormin, Claudia, Bayerl, Anja, Pigorsch, Steffi, Vordermark Dirk, Geinitz Hans, Bölling, Tobias, Wypior Hans, Rittweger, Jutta, Herschbach Peter, Schulze Wolfgang, Vordermark, Dirk, Herschbach, Peter, Boelling, Tobias, Geinitz, Hans, Schaefer, Christof, Zehentmayr, Franz, Zehentmayr Franz, Sehlen, Susanne, Wypior, Hans Joachim, Bayerl Anja, Schulze, Wolfgang, Rittweger Jutta, Dormin Claudia, Pigorsch Steffi, Schäfer, Christof, Schäfer Christof   +27 more
core   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Does CyberKnife improve dose distribution versus IMRT and VMAT on a linear accelerator in low-risk prostate cancer?

Radiology and Oncology, 2022
Hypofractionated stereotactic body radiation therapy (SBRT) for prostate cancer (PCa) can be delivered with the robot-assisted CyberKnife (CK) system or on a linear accelerator using dynamic intensity-modulated radiotherapy (IMRT) or volumetric arc ...
Borowicz Dorota Maria, Skrobała Agnieszka, Kruszyna-Mochalska Marta, Malicki Julian   +3 more
doaj   +1 more source