Results 41 to 50 of about 30,735 (203)

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

Advanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu, Qianru Zhang, Wenqiang Yan, Lu Sun, Yiran Cui, Bolin Liu, Guoqing Han, Feng Zhang, Ke Pu, Mingchao Zhang, Xiaobing Zhang, Qingguo Li, Gang An, Yuxuan Liu   +13 more
wiley   +1 more source

Stereotactic Body Radiotherapy: Prostate Cancer

, 2021
Stereotactic Body Radiotherapy: Prostate Cancer Monica Mahon Dr. Elaine Halesey, Ed.D., R.T.(R)(QM) Abstract Stereotactic body radiotherapy (SBRT) is a special type of radiation therapy that uses very high precise radiation to treat cancerous cells and ...
Mahon, Monica
core  

The use of stereotactic radiotherapy in the treatment of lung malignancies — a scoping review

Oncology in Clinical Practice
INTRODUCTION: Lung cancer remains as main cause of cancer-related mortality, despite new advances, with many patients remaining inoperable. Novel methods of radiotherapy, including stereotactic body radiotherapy (SBRT), can provide survival benefits in ...
Chara Chantzara, Eleni Tzanetou, Hatham El-Ghobashy, Sotiris Christoforou, Datis Kalali   +4 more
doaj   +1 more source

Management of Chordoma and Chondrosarcoma with Fractionated Stereotactic Radiotherapy

Frontiers in Surgery, 2017
ObjectiveTo evaluate the efficacy and toxicity of fractionated stereotactic radiotherapy (FSRT) for chordoma and chondrosarcoma.MethodsTwenty consecutive patients with a histopathologic diagnosis of chordoma (n = 16) or chondrosarcoma (n = 4) treated ...
Harish N. Vasudevan, Harish N. Vasudevan, David R. Raleigh, Julian Johnson, Adam A. Garsa, Philip V. Theodosopoulos, Manish K. Aghi, Christopher Ames, Michael W. McDermott, Igor J. Barani, Steve E. Braunstein   +10 more
doaj   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Acute side effects after definitive stereotactic body radiation therapy (SBRT) for patients with clinically localized or locally advanced prostate cancer: a single institution prospective study

Radiology and Oncology, 2021
The aim of the study was to evaluate acute side effects after extremely hypofractionated intensity-modulated radiotherapy (IMRT) with stereotactic body radiation therapy (SBRT) for definitive treatment of prostate cancer patients.
Jorgo Kliton, Polgar Csaba, Stelczer Gabor, Major Tibor, Gesztesi Laszlo, Agoston Peter   +5 more
doaj   +1 more source

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

Annals of Gastroenterological Surgery, EarlyView.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya, Koichi Yagi, Yoshifumi Baba   +2 more
wiley   +1 more source

Clinical and radiographic response of a paravertebral hemangioma to radiotherapy

Radiology Case Reports
Hemangiomas can arise anywhere in the body. While vertebral hemangiomas are common, atypical hemangiomas with paraspinal and epidural extension are rare. We present a case of a patient who presented with persistent cough and anorexia from a paravertebral
Laura Burgess, MSc, MD, Julia Malone, BSc, Marlise P. dos Santos, MSc,MPH, MD, John Sinclair, MD, Osbert Zalay, MD, PhD, Shawn Malone, MD   +5 more
doaj   +1 more source

Stereotactic Body Radiotherapy for Locally Advanced Pancreatic Cancer Using Optical Surface Management System – AlignRT as an Optical Body Surface Motion Management in Deep Breath Hold Patients: Results from a Single-Arm Retrospective Study

Cancer Management and Research, 2022
Hrvoje Kaučić,1,2 Domagoj Kosmina,3 Dragan Schwarz,4– 6 Andreas Mack,7 Adlan Čehobašić,2,3 Vanda Leipold,2,3 Asmir Avdićević,1 Mihaela Mlinarić,3 Matea Lekić,1 Karla Schwarz,8 Marija Banović9
Kaučić H, Kosmina D, Schwarz D, Mack A, Čehobašić A, Leipold V, Avdićević A, Mlinarić M, Lekić M, Schwarz K, Banović M   +10 more
doaj  

Perfusion imaging of colorectal liver metastases treated with bevacizumab and stereotactic body radiotherapy

Physics and Imaging in Radiation Oncology, 2018
Stereotactic body radiotherapy (SBRT) and bevacizumab are used in the treatment of colorectal liver metastases. This study prospectively evaluated changes in perfusion of liver metastases in seven patients treated with both bevacizumab and SBRT ...
Jay S. Detsky, Laurent Milot, Yoo-Joung Ko, Pablo Munoz-Schuffenegger, William Chu, Gregory Czarnota, Hans T. Chung   +6 more
doaj   +1 more source