Results 41 to 50 of about 50,472 (297)

The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]

, 2010
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y., Stapleton, Christopher J., Weiss, Martin H.   +2 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Does CyberKnife improve dose distribution versus IMRT and VMAT on a linear accelerator in low-risk prostate cancer?

Radiology and Oncology, 2022
Hypofractionated stereotactic body radiation therapy (SBRT) for prostate cancer (PCa) can be delivered with the robot-assisted CyberKnife (CK) system or on a linear accelerator using dynamic intensity-modulated radiotherapy (IMRT) or volumetric arc ...
Borowicz Dorota Maria, Skrobała Agnieszka, Kruszyna-Mochalska Marta, Malicki Julian   +3 more
doaj   +1 more source

Dosimetric validation of a magnetic resonance image gated radiotherapy system using a motion phantom and radiochromic film. [PDF]

, 2017
PurposeMagnetic resonance image (MRI) guided radiotherapy enables gating directly on the target position. We present an evaluation of an MRI-guided radiotherapy system's gating performance using an MRI-compatible respiratory motion phantom and ...
Berbeco, Brady, Chuang, Fayad, Freislederer, Garibaldi, Giraud, Jin, Keall, Kini, Koch, Lewis, Low, Malinowski, Nioutsikou, Ozhasoglu, Sanders, Seppenwoolde, Shiinoki, Shirato, Smith, Tacke, Voort, Wagman, Wiersma, Wojcieszynski, Wunderink, Yoganathan, Yousefi   +28 more
core   +1 more source

Stereotactic Body Radiotherapy for Primary Prostate Cancer [PDF]

Technology in Cancer Research & Treatment, 2018
Prostate cancer is the most common non-cutaneous cancer in males. There are a number of options for patients with localized early stage disease, including active surveillance for low-risk disease, surgery, brachytherapy, and external beam radiotherapy.
Gargi Kothari, Andrew Loblaw, Alison C. Tree, Nicholas J. van As, Drew Moghanaki, Simon S. Lo, Piet Ost, Shankar Siva   +7 more
openaire   +4 more sources

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

The use of stereotactic radiotherapy in the treatment of lung malignancies — a scoping review

Oncology in Clinical Practice
INTRODUCTION: Lung cancer remains as main cause of cancer-related mortality, despite new advances, with many patients remaining inoperable. Novel methods of radiotherapy, including stereotactic body radiotherapy (SBRT), can provide survival benefits in ...
Chara Chantzara, Eleni Tzanetou, Hatham El-Ghobashy, Sotiris Christoforou, Datis Kalali   +4 more
doaj   +1 more source

Management of Chordoma and Chondrosarcoma with Fractionated Stereotactic Radiotherapy

Frontiers in Surgery, 2017
ObjectiveTo evaluate the efficacy and toxicity of fractionated stereotactic radiotherapy (FSRT) for chordoma and chondrosarcoma.MethodsTwenty consecutive patients with a histopathologic diagnosis of chordoma (n = 16) or chondrosarcoma (n = 4) treated ...
Harish N. Vasudevan, Harish N. Vasudevan, David R. Raleigh, Julian Johnson, Adam A. Garsa, Philip V. Theodosopoulos, Manish K. Aghi, Christopher Ames, Michael W. McDermott, Igor J. Barani, Steve E. Braunstein   +10 more
doaj   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source