Results 41 to 50 of about 3,454,417 (246)

Stereotactic Radiotherapy in Uveal Melanoma

, 2014
Uveal melanoma is the most common primary malignant intraocular neoplasm in adults. The aims of treatment of the uveal melanoma are to prevent the metastatic spread of the disease and to preserve as much useful vision as possible.
Ela Delikgöz Soykut, Yıldız Yükselen Güney, Ayşen Dizman   +2 more
core   +1 more source

Re-irradiation: Outcome, cumulative dose and toxicity in patients retreated with stereotactic radiotherapy in the abdominal or pelvic region [PDF]

, 2012
The purpose of the present study was to explore the outcome, cumulative dose in tumor and organs at risk and toxicity after extra-cranial stereotactic re-irradiation.
Hoogeman, M.S. (Mischa), Nuyttens, J.J.M.E. (Joost), Nuyttens, J.J.M.E., Hoogeman, M, Abusaris, H. (Huda), Abusaris, Huda   +5 more
core   +2 more sources

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Clinical and radiographic response of a paravertebral hemangioma to radiotherapy

Radiology Case Reports
Hemangiomas can arise anywhere in the body. While vertebral hemangiomas are common, atypical hemangiomas with paraspinal and epidural extension are rare. We present a case of a patient who presented with persistent cough and anorexia from a paravertebral
Laura Burgess, MSc, MD, Julia Malone, BSc, Marlise P. dos Santos, MSc,MPH, MD, John Sinclair, MD, Osbert Zalay, MD, PhD, Shawn Malone, MD   +5 more
doaj   +1 more source

Stereotactic Body Radiotherapy for Locally Advanced Pancreatic Cancer Using Optical Surface Management System – AlignRT as an Optical Body Surface Motion Management in Deep Breath Hold Patients: Results from a Single-Arm Retrospective Study

Cancer Management and Research, 2022
Hrvoje Kaučić,1,2 Domagoj Kosmina,3 Dragan Schwarz,4– 6 Andreas Mack,7 Adlan Čehobašić,2,3 Vanda Leipold,2,3 Asmir Avdićević,1 Mihaela Mlinarić,3 Matea Lekić,1 Karla Schwarz,8 Marija Banović9
Kaučić H, Kosmina D, Schwarz D, Mack A, Čehobašić A, Leipold V, Avdićević A, Mlinarić M, Lekić M, Schwarz K, Banović M   +10 more
doaj  

Acute side effects after definitive stereotactic body radiation therapy (SBRT) for patients with clinically localized or locally advanced prostate cancer: a single institution prospective study

Radiology and Oncology, 2021
The aim of the study was to evaluate acute side effects after extremely hypofractionated intensity-modulated radiotherapy (IMRT) with stereotactic body radiation therapy (SBRT) for definitive treatment of prostate cancer patients.
Jorgo Kliton, Polgar Csaba, Stelczer Gabor, Major Tibor, Gesztesi Laszlo, Agoston Peter   +5 more
doaj   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Advances of Precise Radiotherapy for Lung Cancer

Chinese Journal of Lung Cancer, 2011
At present lung tumor radiation therapy has entered the accurate radiotherapy era. Precise radiotherapy includes intensity modulated radiotherapy (IMRT), image-guided radiotherapy (IGRT) and stereotactic body radiotherapy (SBRT).
Xin WANG, Feng XU, Yuquan WEI
doaj   +1 more source

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

Clinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit, Maaike van Dartel, Laura Rodwell, Hanneke van der Woude, Cornelis Boersma, Peter G. M. Mol, Doranne Hilarius   +6 more
wiley   +1 more source

Epigenetic modification in radiotherapy and immunotherapy for cancers

Tzu Chi Medical Journal
Radiotherapy (RT) is one of the primary treatment modalities in managing cancer patients. Recently, combined RT and immunotherapy (IT) (i.e., radio-IT [RIT]) have been aggressively investigated in managing cancer patients.
Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Dai-Wei Liu, Chih-Chia Yu, Liang-Cheng Chen, Ru-Inn Lin, Chia-Hui Chew, Feng-Chun Hsu, Hsuan-Ju Yang, Michael W. Y. Chan, Hon-Yi Lin   +11 more
doaj   +1 more source