Results 41 to 50 of about 41,093 (226)

Pseudoprogression after Stereotactic Body Radiotherapy [PDF]

Journal of Thoracic Oncology, 2014
Journal of Thoracic Oncology ® • Volume 9, Number 4, April 2014 Stereotactic body radiotherapy (SBRT) is a highly conformal treatment modality that uses image guidance to allow precise delivery of ablative doses of radiation to a target, resulting in excellent local control with minimal toxicity.
Frechette, Kelsey M., Brown, Lindsay C., Aubry, Marie C., Wigle, Dennis A., Olivier, Kenneth R.   +4 more
openaire   +2 more sources

Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study

Radiation Oncology, 2009
Background A phase III multi-centre randomised trial (ROSEL) has been initiated to establish the role of stereotactic radiotherapy in patients with operable stage IA lung cancer. Due to rapid changes in radiotherapy technology and evolving techniques for
van der Heide Uulke A, Widder Joachim, Lagerwaard Frank J, Cuijpers Johan P, Hurkmans Coen W, Schuring Danny, Senan Suresh   +6 more
doaj   +1 more source

Stereotactic radiotherapy is a useful treatment option for patients with medullary thyroid cancer

BMC Endocrine Disorders, 2021
The role of radiotherapy in advanced medullary thyroid carcinoma (MTC) is confined to patients in whom surgical treatment or the administration of tyrosine kinase inhibitors are not possible or contraindicated.
Aleksandra Kukulska, Jolanta Krajewska, Zofia Kołosza, Aleksandra Grządziel, Mateusz Gajek, Ewa Paliczka-Cieślik, Dorota Syguła, Kornelia Ficek, Aneta Kluczewska-Gałka, Barbara Jarząb   +9 more
doaj   +1 more source

Successful Treatment of Adenoid Cystic Carcinoma with the Application of a High-Dose Stereotactic Body Radiotherapy Boost

Case Reports in Oncology, 2021
Background: Adenoid cystic carcinoma (ACC) should be treated with a surgical procedure. Unfortunately, in some cases, such procedures are impossible to perform.
Paweł Polanowski, Dorota Księżniak-Baran, Aleksandra Grządziel, Agnieszka Pietruszka, Ewa Chmielik, Bolesław Pilecki, Natalia Amrogowicz, Karolina Gajda, Krzysztof Składowski   +8 more
doaj   +1 more source

An optimal dose‐fractionation for stereotactic body radiotherapy in peripherally, centrally and ultracentrally located early‐stage non‐small lung cancer

Thoracic Cancer, 2023
Stereotactic body radiotherapy (SBRT), also known as stereotactic ablative radiotherapy (SABR), is commonly used in inoperable patients with early‐stage non‐small lung cancer (NSCLC).
Izabela Zarębska, Maciej Harat
doaj   +1 more source

The Role of Stereotactic Radiotherapy in the Management of Melanoma, A Retrospective Single Institute Preliminary Study of 30 Patients

Pathology and Oncology Research, 2022
Cutaneous melanoma is the third most common type of skin cancer in the world. The incidence of melanoma is increasing in most countries, however, mortality seems to be slowly decreasing.
Mihály Kispál, Levente Zsolt Jánváry, Tímea Balatoni, Stelczer Gábor, Imre Fedorcsák, Bőcs Katalin, István Kenessey, Gabriella Liszkay   +7 more
doaj   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Feasibility of proton transmission-beam stereotactic ablative radiotherapy versus photon stereotactic ablative radiotherapy for lung tumors: a dosimetric and feasibility study. [PDF]

PLoS ONE, 2014
Stereotactic ablative radiotherapy is being increasingly adopted in the treatment of lung tumors. The use of proton beam therapy can further reduce dose to normal structures.
Benjamin Mou, Chris J Beltran, Sean S Park, Kenneth R Olivier, Keith M Furutani   +4 more
doaj   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

Clinical Outcomes and Prognostic Factors of Stereotactic Radiotherapy for Spinal Metastases With Epidural Spinal Cord Compression Grades 1-2. [PDF]

Cancer Med
ABSTRACT Objective Investigate the efficacy of stereotactic radiotherapy in patients with metastatic tumors accompanied by epidural spinal cord compression (ESCC) of Grades 1–2 but without vertebral instability who did not undergo surgery. Methods Based on lesion volume and spinal cord compression degree, SBRT doses of 24 Gy/1f, 30 Gy/3f, and 40 Gy/5f ...
Zhuang H, Xiao Y, Li J, Wang Y, Cheng C, Tao L, Wei F, Liu Y.   +7 more
europepmc   +2 more sources