Results 61 to 70 of about 42,899 (196)

Epigenetic modification in radiotherapy and immunotherapy for cancers

Tzu Chi Medical Journal
Radiotherapy (RT) is one of the primary treatment modalities in managing cancer patients. Recently, combined RT and immunotherapy (IT) (i.e., radio-IT [RIT]) have been aggressively investigated in managing cancer patients.
Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Dai-Wei Liu, Chih-Chia Yu, Liang-Cheng Chen, Ru-Inn Lin, Chia-Hui Chew, Feng-Chun Hsu, Hsuan-Ju Yang, Michael W. Y. Chan, Hon-Yi Lin   +11 more
doaj   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

Precision Radiation Oncology, EarlyView.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu, Yang Zhang, Zuomin Wang, Zongjuan Li, Shisuo Du   +4 more
wiley   +1 more source

The use of stereotactic radiotherapy in the treatment of lung malignancies — a scoping review

Oncology in Clinical Practice
INTRODUCTION: Lung cancer remains as main cause of cancer-related mortality, despite new advances, with many patients remaining inoperable. Novel methods of radiotherapy, including stereotactic body radiotherapy (SBRT), can provide survival benefits in ...
Chara Chantzara, Eleni Tzanetou, Hatham El-Ghobashy, Sotiris Christoforou, Datis Kalali   +4 more
doaj   +1 more source

Nomogram integrating MRI radiomics and white matter hyperintensity grading for predicting overall survival in patients with non‐small cell lung cancer and brain metastases receiving whole‐brain radiotherapy

Precision Radiation Oncology, EarlyView.
A prognostic nomogram integrating radiomic features and white matter hyperintensity (WMH) grading was developed to enable individualized survival prediction in patients with brain metastases (BMs). Integration of these imaging biomarkers into the clinical model enhanced predictive performance, indicating their incremental prognostic value for BM ...
Jianan Ni, Yuefeng Lu, Haoli Xu, Xuni Xu, Mengjing Zhao, Yingnan Xue, Gang Li, Yuxia Duan   +7 more
wiley   +1 more source

Stereotactic radiotherapy for wet age-related macular degeneration: current perspectives

Clinical Ophthalmology, 2015
James E Neffendorf, Timothy L Jackson Department of Ophthalmology, School of Medicine, King’s College London, London, United Kingdom Abstract: Neovascular age-related macular degeneration is a leading cause of blindness in the developed world ...
Neffendorf JE, Jackson TL
doaj  

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent high‐grade glioma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 495-509, March 2025.
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar, Solmaz Sahebjam, Hsiang‐Husan M. Yu, Dung‐Tsa Chen, Menal Bhandari, Heiko Enderling   +5 more
wiley   +1 more source

Prophylactic Cranial Irradiation Versus Active MRI Surveillance in Small Cell Lung Cancer: Systematic Review and Meta‐Analysis

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background Prophylactic cranial irradiation (PCI) has traditionally been a cornerstone of treatment in limited‐stage and extensive‐stage small cell lung cancer (SCLC). Recent evidence suggests that active MRI brain surveillance may result in comparable overall survival (OS) and progression‐free survival (PFS).
Zhao Feng Liu, Amy Sylivris, Yuan‐Hong Lin, Jennifer Ward, Marcus Cheng, Jodie Tham, Gemma D'Adamo, Sashendra Senthi   +7 more
wiley   +1 more source

Interventional Radiology Society of Australasia Quality Care Guidelines for Renal Tumour Ablation in Australia and New Zealand

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Image‐guided thermal ablation (radiofrequency, cryo‐ and microwave ablation) is a safe and effective primary treatment for small renal mass and localised renal cell carcinoma ≤ 4 cm (T1a) with long‐term cancer‐specific survival rates equivalent to surgical resection (Level A).
Matthew Lukies, William Ormiston, Nicholas Brown, Philip Chan, Ahmad Al‐Hindawi, Radha Popuri, Brendan Buckley   +6 more
wiley   +1 more source

Lung V5 and Planning Target Volume/Lung Volume Ratio as Independent Risk Factors for ≥Grade 2 Radiation Pneumonitis after Moderately Hypofractionated Radiotherapy: A Retrospective Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung V5 and the planning target volume/lung volume ratio were identified as independent dosimetric risk factors for clinically significant radiation pneumonitis following moderately hypofractionated radiotherapy for lung cancer. Maintaining V5 < 35% may help mitigate this risk in clinical practice.
YuanYou Yang, FengXia Luo, Chao Wang, Gang Ren   +3 more
wiley   +1 more source