Results 71 to 80 of about 52,263 (284)

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

Advanced Science, EarlyView.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez, Suguru Ogata, Xiaoping Wang, Naoto T. Ueno   +3 more
wiley   +1 more source

Retrospective study on the toxicity induced by stereotactic body radiotherapy: overview of the reunion experience on prostate cancer in elderly patients

Frontiers in Oncology
IntroductionProstate cancer is the fourth most commonly diagnosed cancer among men worldwide. Various tools are used to manage disease such as conventional radiotherapy.
Youssef Slama, Gilles Baumont, Angelique Arcambal, Mickael Begue, Olivier Maillot, Rima Sayah, Romain Castanet, Raoul Caboche, Pedro Liberati, Hakim Slaoui, Medi Bouaziz, Olivier Borson, Nam P. Nguyen, Fabien Dutheil   +13 more
doaj   +1 more source

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

Annals of Gastroenterological Surgery, EarlyView.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya, Koichi Yagi, Yoshifumi Baba   +2 more
wiley   +1 more source

Stereotactic radiotherapy in oligometastatic cancer

Chinese Clinical Oncology, 2017
Oligometastatic cancer describes a disease state somewhere between localized and metastatic cancer. Proposed definitions of oligometastatic disease have typically used a cut-off of five or fewer sites of disease. Treatment of oligometastatic disease should have the goal of long-term local control, and in selected cases, disease remission. While several
Thomas A C, Kennedy, Mark T, Corkum, Alexander V, Louie   +2 more
openaire   +2 more sources

Stereotactic body radiotherapy in the era of radiotherapy with immunotherapy [PDF]

Journal of Thoracic Disease, 2016
The spectrum of clinical use of stereotactic body radiotherapy (SBRT), also known as stereotactic ablative radiotherapy (SABR) has broaden, which has drawn much attention beyond radiation oncologists (1). Immunology and immunotherapy has been considered to provide curative potential for cancer therapy by key opinion leaders globally in recent years (2).
Xiaolin, Ge, Hongcheng, Zhu, Wangshu, Dai, Xinchen, Sun   +3 more
openaire   +2 more sources

Reirradiation and stereotactic radiotherapy for tumors in the lung: Dose summation and toxicity

, 2013
Purpose: To assess the accumulated dose and the toxicity after reirradiation for tumors in the lung using non-rigid registration. Material and methods: Twenty patients with a tumor in the lung were reirradiated with or after stereotactic radiotherapy ...
Meijneke, TR, Petit, Steven, Nuyttens, J.J.M.E., Hoogeman, M, Wentzler, D (Davy)   +4 more
core   +1 more source

Magnetic resonance imaging for brain stereotactic radiotherapy

, 2020
Due to its superior soft tissue contrast, magnetic resonance imaging (MRI) is essential for many radiotherapy treatment indications. This is especially true for treatment planning in intracranial tumors, where MRI has a long-standing history for target ...
Perrin, Rosalind, Bäuerle, Tobias, Dörfler, Arndt, Weissmann, Thomas, Mengling, Veit, Doussin, Sylvain, Schmidt, Manuel Alexander, Janka, Rolf, Fietkau, Rainer, Rösch, Johannes, Putz, Florian, Masitho, Siti, Lettmaier, Sebastian, Cavallaro, Alexander, Bert, Christoph, Uder, Michael, Semrau, Sabine, Amarteifio, Patrick   +17 more
core   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Considerations regarding carotid artery dose in radiotherapy of the cervical spine

Clinical and Translational Radiation Oncology, 2023
Radiation to the carotid arteries, e.g. in the context of head and neck cancer treatment, is one of several risk factors for artery stenosis. In principle, this fact may also have implications for stereotactic cervical spine radiotherapy, because long ...
Carsten Nieder, David McKenzie Grant
doaj   +1 more source

Clinicogenomic Features and Outcomes of Adenoid Cystic Carcinoma With Central Nervous System Metastases: A Single‐Institution Cohort Study

Head &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is a rare malignancy with a propensity for perineural invasion and hematogenous spread. Central nervous system (CNS) involvement is uncommon, and detailed clinical and genomic data on this aspect of the disease remain limited.
Omar Elghawy, Jack Stylli, Martin Kurian, Eitan Halper‐Stromberg, Aditi Singh, Christopher D'Avella, Lee Hartner, Roger B. Cohen   +7 more
wiley   +1 more source