Results 81 to 90 of about 42,899 (196)

Descriptive analysis of screen‐detected versus clinically diagnosed lung cancer cases: evidence of earlier stage shift and treatment differences

Internal Medicine Journal, EarlyView.
Abstract Background Lung cancer is the leading cause of cancer‐related deaths worldwide, largely due to late‐stage diagnosis. Lung cancer screening by computed tomography (CT) reduces mortality by detecting cancers earlier in high‐risk individuals, prompting Australia to launch the National Lung Cancer Screening Program (NLCSP) in 2025.
Jazmin Guayco Sigcha, Tian Mun Chee, Ian A. Yang, Linda Passmore, Kwun M. Fong, Henry M. Marshall   +5 more
wiley   +1 more source

Survival outcomes in dogs treated with vinorelbine‐based adjuvant treatment following surgical resection of grade II and III pulmonary carcinoma

Journal of Small Animal Practice, EarlyView.
Objectives Pulmonary carcinoma in dogs is commonly managed with surgical resection; however, the role of adjuvant chemotherapy for grade II and III carcinomas remains unclear. This retrospective multicentre study investigated the outcomes in dogs treated with vinorelbine‐based adjuvant treatment (as monotherapy or combined chemotherapy) following ...
N. Wong, L. Brockley, S. Rajan, J. Yu
wiley   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

The Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?

Head &Neck, Volume 48, Issue 9, Page 2541-2556, September 2026.
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan, Avraham Eisbruch, June Corry, Sandra Nuyts, Pim de Graaf, Luiz P. Kowalski, Jonathan J. Beitler, Sweet Ping Ng, William M. Mendenhall, M. P. Sreeram, Karthik N. Rao, Anna Luíza Damaceno Araújo, Alfio Ferlito   +12 more
wiley   +1 more source

Integrating Immunotherapy Into Head and Neck Surgery: Bridging Tumor Biology to Perioperative Decision‐Making, a Review

Head &Neck, Volume 48, Issue 9, Page 2570-2583, September 2026.
ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
wiley   +1 more source

Urethral Metastasis of Therapy‐Induced Neuroendocrine Prostate Cancer Successfully Managed With Chemoradiotherapy: A Case Report

IJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Introduction Urethral metastasis of prostate cancer is exceptionally rare, particularly in castration‐resistant disease. Therapy‐induced neuroendocrine prostate cancer (t‐NEPC) is an aggressive variant with limited treatment options. Case Presentation A 72‐year‐old man, 14 years after diagnosis of prostate adenocarcinoma treated with androgen ...
Toshiaki Kayaba, Satoshi Washino, Takanori Hayase, Kai Yazaki, Kimitoshi Saito, Tomoaki Miyagawa   +5 more
wiley   +1 more source

Stereotactic radiotherapy with Gamma Master System® for palliation of hepatocellular carcinoma in patients with liver cirrhosis

Radiation Oncology
Background Stereotactic radiotherapy with Gamma Master System® delivered for portal vein tumor thrombosis (PVTT) located in the main portal vein is previously exploited.
Bin Qiu, Fang Fang, Peng Zhen, Junjie Wang   +3 more
doaj   +1 more source

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Continuing Professional Development—Radiation Therapy

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 174-174, March 2025.
wiley   +1 more source