Results 121 to 130 of about 9,285,009 (287)

Acurácia diagnóstica da biópsia percutânea com agulha grossa orientada por estereotaxia nas lesões mamárias categoria BI-RADS® 4 Diagnostic accuracy of stereotactic core-needle biopsy of non-palpable breast lesions categorized as BI-RADS® 4

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2007
OBJETIVO: avaliar a acurácia da biópsia com agulha grossa (BAG) orientada por estereotaxia nas lesões mamárias categoria BI-RADS® 4. MÉTODOS: realizou-se uma análise retrospectiva das lesões categoria BI-RADS® 4 que foram submetidas à BAG orientada por ...
Maria Silvia Petty Moutinho   +4 more
doaj   +1 more source

Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]

open access: yes, 2004
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core  

Perampanel as a second‐line therapy to midazolam reduces soman‐induced status epilepticus and neurodegeneration in rats

open access: yesEpilepsia Open, EarlyView.
Abstract Objective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset. Preclinical studies showed that benzodiazepines were less effective in stopping status epilepticus when treatment was ...
Hailey G. Steier   +8 more
wiley   +1 more source

Adaptable three-pin skull clamp for large animal research

open access: yesHardwareX, 2023
Traditionally, surgical head immobilization for neurobiological research with large animals is achieved using stereotaxic frames. Despite their widespread use, these frames are bulky, expensive, and inflexible, ultimately limiting surgical access and ...
Maxwell Lohss   +6 more
doaj  

Impaired Volume Regulation and Electrophysiology of Astrocytes In Situ in a Mouse Model for Megalencephalic Leukoencephalopathy With Subcortical Cysts

open access: yesGlia, EarlyView.
Cell culture studies show disrupted astrocyte physiology in the leukodystrophy MLC. Are intact astrocytes similarly affected? This study on astrocytes in MLC mouse brain slices confirms and extends in vitro studies on altered astrocyte physiology. ABSTRACT Electrical signaling, driven by ion fluxes between intra‐ and extracellular compartments, is ...
Sven Kerst   +5 more
wiley   +1 more source

Three-dimensional atlas system for mouse and rat brain imaging data

open access: yesFrontiers in Neuroinformatics, 2007
Tomographic neuroimaging techniques allow visualization of functionally and structurally specific signals in the mouse and rat brain. The interpretation of the image data relies on accurate determination of anatomical location, which is frequently ...
Trine Hjornevik   +8 more
doaj   +1 more source

Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects

open access: yesInterdisciplinary Medicine, EarlyView.
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu   +9 more
wiley   +1 more source

Losing brain networks during death

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Death represents the end of all living organisms. The pattern of brain activity disappearance following death, however, has not been fully elucidated. Here we investigated brain activity dynamics following cardiac arrest using ultra‐high field 11.7 T magnetic resonance imaging (MRI) in longitudinal approach and multi‐modal analyses. Initially,
Han Li   +22 more
wiley   +1 more source

Assessing the risk of central post-stroke pain of thalamic origin by lesion mapping [PDF]

open access: yes, 2017
Central post-stroke pain of thalamic origin is an extremely distressing and often refractory disorder. There are no well-established predictors for pain development after thalamic stroke, and the role of different thalamic nuclei is unclear.
Andreou, Anna P.   +9 more
core  

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

open access: yesSmall, EarlyView.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun   +12 more
wiley   +1 more source

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