Results 151 to 160 of about 9,592,818 (278)

Aβ antibodies target not only amyloid plaques but also distinct brain cells and vessels

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract BACKGROUND Amyloid beta (Aβ) antibodies are the only therapies to slow cognitive decline in Alzheimer's disease (AD). Yet the sites where antibodies engage Aβ in the brain and mechanisms that lower Aβ are not fully understood. Defining Aβ antibody localizations in the brain is essential to understand how immunotherapy is beneficial for AD ...
Gehua Wen, Nils Lindblom, Xiaoni Zhan, Megg Garcia‐Ryde, Tomas Deierborg, Asgeir Kobro‐Flatmoen, Gunnar K. Gouras   +6 more
wiley   +1 more source

Combination of Averaged Bregma-Interaural and Electrophysiology-Guided Technique Improves Subthalamic Nucleus Targeting Accuracy in Rats. [PDF]

eNeuro
Deng Z, Awada A, Kilic U, Mc Laughlin M, Baunez C, Nuttin B.   +5 more
europepmc   +1 more source

Genetic Association Between Polymyositis/Dermatomyositis and Epilepsy: Insights From Mendelian Randomization and Bioinformatic Analyses

Brain and Behavior, Volume 16, Issue 1, January 2026.
This Mendelian randomization study provides robust evidence for a causal link between polymyositis (PM) and epilepsy, highlighting the role of immune‐mediated mechanisms in epilepsy development, while no such association was found for dermatomyositis (DM). Through bioinformatic and statistical analyses, key genes and pathways were identified, with IER3,
Ying Liu, Yuhang Yu, Chulong Fang, Qingzhong Wu, Lingli Ou, Jianhao Xiao, Kui Duan, Ting Jiang, Lan Ye, Xiao Hu, Zhanhui Feng   +10 more
wiley   +1 more source

Longitudinal calcium imaging of BNST neurons in mice during optogenetic manipulation of paraventricular thalamus axon terminals. [PDF]

STAR Protoc
Mindaye SA, Chen WH, Lin SC, Chen CC.
europepmc   +1 more source

AFNI: software for analysis and visualization of functional magnetic resonance neuroimages.

Computers and biomedical research, an international journal, 1996
R. Cox
semanticscholar   +1 more source

The Enigma of Neuromelanin: How Animal Models Can Help Researchers to Understand the Link Between Pigments and Neurodegeneration. [PDF]

Biomedicines
Esser S, Hausherr M, Marcus-Alic K.
europepmc   +1 more source

PGC‐1α Transcriptionally Regulated by ChREBP Mitigates Neuropathic Pain Through Promoting Microglial Fatty Acid Oxidation and Anti‐Inflammatory Response

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
ChREBP transcriptionally regulates PGC‐1α, which enhances the expression of fatty acid oxidation genes, promotes the fatty acid oxidation process, and thereby increases the polarization of anti‐inflammatory microglia, reduces the level of inflammatory factors, and improves pain symptoms.
Ziwei Hu, Jiahui Pang, Xinli Liu, Yun Zhao, Yi Lu, Hui Chen, Hui Zeng, Youxin Yu, Yubai Zhao, Lijie Gao, Xuefei Zhang, Jian Jin, Kangling Wang, Yu Shi, Hongrui Zhan, Wen Wu   +15 more
wiley   +1 more source

TTBK2‐Driven Ciliogenesis Is Required for Intrinsic Neuronal Regeneration After Spinal Cord Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
TTBK2‐dependent ciliogenesis is required for intrinsic neuronal regeneration after spinal cord injury. Loss of TTBK2 disrupts primary cilium integrity, attenuates SHH signaling, and impairs axonal regrowth. Restoring SHH activity partially rescues neuronal structural deficits, highlighting the TTBK2/cilium–SHH as a therapeutic target.
Renfeng Zhang, Su Pan, Zhenwei Tian, Haorui Du, Jintao Wang, Xiaoyu Yang, Zhiping Qi   +6 more
wiley   +1 more source

Curved trajectories in stereotactic neurosurgery: is it feasible? [PDF]

Neurosurg Rev
Keiner D, Mühlenhoff J, Henia M, Rabel F, Reith W, Hoffmann MK, Flaßkamp K, Worthmann K, Sattel T, Oertel J.   +9 more
europepmc   +1 more source

Aerobic fitness reduces brain tissue loss in aging humans.

The journals of gerontology. Series A, Biological sciences and medical sciences, 2003
S. Colcombe, K. Erickson, N. Raz, Andrew G. Webb, N. Cohen, E. McAuley, A. Kramer   +6 more
semanticscholar   +1 more source