Results 151 to 160 of about 9,285,009 (287)
Alterations in the expression levels of D2S and D2L resulted in obesity and metabolic syndrome such as abdominal fat accumulation and hyperglycemia in D2L KO mice fed with a high‐fat diet, compared to WT mice. This may be partly due to increased food intake.
Hanna Gonzalez+5 more
wiley +1 more source
Neural electrodes were modified with poly(3,4‐ethylenedioxythiophene) (PEDOT) doped with chondroitin sulfate or dextran sulfate. Electrochemical and acute electrophysiological recordings were undertaken. The effective electrode area had the strongest correlation with electrophysiological response.
Alexander R. Harris+2 more
wiley +1 more source
Orexinergic neurons contribute to autonomic cardiovascular regulation for locomotor exercise
Abstract figure legend This study unveiled the essential role of the orexinergic nervous system in the central circuitry that transmits central command signals for locomotor exercise. We observed the excitation of orexinergic neurons by voluntary locomotor exercise in rats.
Emi Narai+7 more
wiley +1 more source
Introducción y objetivos. Los métodos actuales de ablación conllevan sistemas de navegación manual y ablación cardiaca, y presentan ciertas limitaciones.
JESÚS RUIZ-ARAGÓN+3 more
doaj
Abstract figure legend The majority of L4–L5 dorsal root ganglion cells innervating the triceps surae muscles of healthy rats expressed TRPC6 channels. In decerebrated rats, pharmacological inhibition of TRPC6 channels by injection of antagonists (SAR7334 or BI‐749327) into the arterial supply of the triceps surae muscles inhibited the exercise pressor
Guillaume P. Ducrocq+5 more
wiley +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen+5 more
wiley +1 more source
Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine
Main Points Astroglial CB1 mediate long‐term depression in the NAc through purine release. Amphetamine occludes LTD in male mice by inducing the saturation of A1 receptors. Astroglial CB1 mediate behavioral amphetamine effects in males, but not in females.
Yamuna Mariani+15 more
wiley +1 more source
Nutritionally Responsive PMv DAT Neurons Are Dynamically Regulated During Pubertal Transition
The ventral premammillary nucleus of the hypothalamus plays an essential role in the metabolic control of reproduction. Puberty brings large changes to a subpopulation of PMvLepRb cells expressing the dopamine transporter (PMvDAT). DAT gene expression is higher in prepubertal females than in adults and is regulated by leptin in prepubertal females ...
Cristina Sáenz de Miera+11 more
wiley +1 more source
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li+16 more
wiley +1 more source