Results 171 to 180 of about 38,147 (287)

A technique of measuring the precision of an MR-guided stereotaxic installation using anatomic specimens.

, 1994
Didier Dormont, Michel Zérah, Philippe Cornu, Fabrice Parker, Bernard Aubert, R. Sigal, J P Francke, A. Zouaoui, C. Marsault   +8 more
openalex   +1 more source

GABAergic Neuron Activation in the RMTg‐VTA Pathway Modulates Dopaminergic Neuron Excitability and Social Stress Susceptibility in Male Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
In susceptible mice, dopamine neurons in the VTA exhibit increased excitability along with upregulation of GABAA receptors. Administration of the GABAA receptor agonist muscimol reduces this neuronal hyperexcitability and reverses social avoidance behavior.
Guang‐Yue Ma, Jin‐Zhu Zhuang, Shu‐Feng Li, Yu‐E Zhang, Di Zhang, Jun Zhao, Zhen Peng, Liu Yang, Zhang Cao, Xin Xie, Rong Jiang, Hui Sun   +11 more
wiley   +1 more source

The Mechanism Underlying the Abnormal Expression of α‐Synuclein in the Cortical Lesions of Patients With FCD Type IIb and TSC

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
The mTOR/GLT‐1 pathway abnormality induces α‐synucleinopathy, contributing to seizures in FCD lesions, which were rescued by treatment with the mTOR inhibitor Rapa or the GLT‐1 enhancer Cef. Intracerebroventricular α‐syn administration attenuated PTZ‐induced seizures in FCD models.
Li Zhang, Jian‐Ping Song, Jun Huang, Ping Liang, Hui Yang, Chun‐Qing Zhang, Kai‐Feng Shen   +6 more
wiley   +1 more source

Establishment and validation of an orthotopic brain metastasis tumor model in C57BL/6 mice. [PDF]

PeerJ
Liu J, Lin T, Wang J, Hao J, Wu W, Zheng Z, Ou H, Liu Y.   +7 more
europepmc   +1 more source

Whole‐Brain Neural Connectivity to Cholinergic Neurons in the Lower Thoracic Intermediolateral Column

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
This study establishes a whole‐brain monosynaptic input map to cholinergic neurons in the lower thoracic intermediolateral column (IML) using a cell‐type‐specific retrograde rabies tracing system in ChAT‐Cre mice. Our results reveal a widespread supraspinal network originating from five major brain divisions, including the telencephalon, diencephalon ...
Yuan‐jun Yang, Kai‐ying Zhang, Bin‐bin Li, Xia‐wan Liu, Jing‐rong Li, Yi‐nuo Liu, Yu‐han Liu, Ji Li, Xiang‐shan Yuan, Ming Zhong   +9 more
wiley   +1 more source

Inhaled 5‐HT1B/1D Receptor Antagonist Attenuates Sumatriptan‐Induced Sensitization of Capsaicin‐Sensitive Lung Vagal Afferents: Implications for Preventing Sumatriptan‐Associated Adverse Chest Symptoms

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Our previous study suggests that sumatriptan‐induced chest discomfort is associated with hypersensitivity of CSLV afferents via 5‐HT1B/1D receptors on nerve endings. The present study demonstrates that inhaled 5‐HT1B/1D receptor antagonism suppresses this hypersensitivity without compromising antimigraine efficacy, supporting local pulmonary antagonism
Nai‐Ju Chan, Zung Fan Yuan, Chang‐Chih Kuo, Chun‐Chun Hsu   +3 more
wiley   +1 more source

Whole-brain efferent projections of glutamatergic neurons in the cingulate cortex of mice. [PDF]

Mol Brain
Shi F, Lei L, Qiu J, Zhu Y, Wu H, Wu X.
europepmc   +1 more source

Using FoxP2 to Distinguish Direct and Indirect Basal Ganglia Pathways for Vocal Learning in Songbirds

Developmental Neurobiology, Volume 86, Issue 2, April 2026.
ABSTRACT The cortico‐basal ganglia pathways that mediate vocal learning in zebra finches (Taeniopygia guttata) are localized in parallel circuits formed by CORE and SHELL subregions. These circuits traverse a specialized region of the basal ganglia essential for vocal learning (Area X), which includes intermixed striatal and pallidal neurons.
Aditi Jagannathan, Mira Nigudkar, Sarah W. Bottjer   +2 more
wiley   +1 more source

Synchrotron‐generated microbeams as a radiosurgical alternative for drug‐resistant epilepsies: Proof of concept in a mouse model of mesiotemporal lobe epilepsy

Epilepsia, Volume 67, Issue 4, Page 1614-1626, April 2026.
Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens, Camille Beets, Clothilde Courivaud, Sarvenaz Keshmiri, Jean‐François Adam, Paolo Pellicioli, Emmanuel Luc Barbier, Raphaël Serduc, Antoine Depaulis   +8 more
wiley   +1 more source

Positron Emission Tomography (PET)-guided stereotaxic brain biopsy: report of the technique and preliminary results.

, 1992
Luc Bidaut
openalex