Results 151 to 160 of about 38,147 (287)

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Human iPSC‐derived GABAergic interneuron transplantation restores circuit balance and cognitive function in an Alzheimer's disease model

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is characterized by disrupted excitatory–inhibitory (E:I) balance and impaired synaptic function, yet current treatments fail to repair these fundamental circuit impairments. METHODS Human induced pluripotent stem cell‐derived post‐mitotic medial ganglionic eminence‐originated inhibitory neurons (MGE‐pINs)
Xinzhe Zhang, Gaojie Wang, Haodong Chen, Ye Sun, Ziteng Wangliu, Lijing Wang, Miao Sun, Qing Liu, Xue Zhang   +8 more
wiley   +1 more source

Bioimaging of sense organs and the central nervous system in extant fishes and reptiles in situ: A review

The Anatomical Record, Volume 309, Issue 4, Page 826-852, April 2026.
Bioimaging of the sense organs and brain of fishes and reptiles. Left panel: 3D reconstruction of the head and brain of the deep‐sea viperfish Chauliodus sloani following diceCT. Right panel: A 3D reconstruction of a 70‐day‐old embryo head of the bearded dragon Pogona vitticeps following diceCT, showing the position of the segmented brain within the ...
Shaun P. Collin, Kara E. Yopak, Jenna M. Crowe‐Riddell, Victoria Camilieri‐Asch, Caroline C. Kerr, Hope Robins, Myoung Hoon Ha, Annalise Ceddia, Travis L. Dutka, Lucille Chapuis   +9 more
wiley   +1 more source

Protocol for the precise activation of intradental neurons in mice via electrical stimulation. [PDF]

STAR Protoc
Wan S, Ronan EA, Jha A, Gandhi AR, Constantinescu BSC, Pipe KP, Emrick JJ.   +6 more
europepmc   +1 more source

Reticulocalbin‐2 in the Hippocampus Improves Cognitive Function of Diabetic Mice

Brain and Behavior, Volume 16, Issue 4, April 2026.
Diabetes reduces hippocampal reticulocalbin‐2 (RCN2) expression, leading to increased GSK3β activity and Tau hyperphosphorylation, resulting in synaptic loss, neurofibrillary tangles, and cognitive decline associated with Alzheimer's pathology. We found that overexpression of RCN2 in the hippocampus partially rescued the cognitive decline and showed ...
Ting Zhang, Simiao Tang, Jiahui Cheng, Biao Hu, Ling‐Qi Xie, Yalun Cheng, Xin Chen, Genqing Xie   +7 more
wiley   +1 more source

Selective genetic targeting of the mouse efferent vestibular nucleus identifies monosynaptic inputs and indicates function as multimodal integrator. [PDF]

J Neurophysiol
Mathews MA, Tung VWK, Reader-Harris EC, Murray AJ.   +3 more
europepmc   +2 more sources

Measurement of brain volume using MRI:software, techniques, choices and prerequisites [PDF]

, 2010
Keller, Simon S., Roberts, Neil
core  

Immature Excitatory Neurons in the Postnatal Ferret Paralaminar Nuclei and Their Relationship to the Amygdala Across Species

Journal of Comparative Neurology, Volume 534, Issue 4, April 2026.
Left: Schematic of a coronal section of the adult ferret brain, showing the location of a collection of Dcx+ cells (green) ventrally to the amygdala (grey) in a region homologous to the PL in other species. These cells are spatially distributed either as individual cells in a dispersed field or in clusters (1). Cells in the ferret PL display molecular (
Lucía Inés Torrijos‐Saiz, Marco Ghibaudi, Malaz Sharief, Lovisa Ljungqvist Brinson, Arturo Alvarez‐Buylla, José Manuel García‐Verdugo, Vicente Herranz‐Pérez, Shawn Sorrells   +7 more
wiley   +1 more source

Intrahippocampal injection in mice used for experimental studies in Alzheimer's disease: a challenging procedure for neuroscience purposes. [PDF]

J Med Life
Laslo A, Laslo L, Brinzaniuc K.
europepmc   +1 more source

Intracranial glioma xenograft model rapidly reestablishes blood–brain barrier integrity for longitudinal imaging of tumor progression using fluorescence molecular tomography and contrast agents [PDF]

, 2020
Achilefu, Samuel, Carpenter, Julia, Chen, Hong, Habimana-Griffin, LeMoyne, Marsala, Lynne, Mixdorf, Matthew, Prior, Julie, Rubin, Joshua B., Sudlow, Gail, Ye, Dezhuang   +9 more
core   +1 more source