Results 51 to 60 of about 51,643 (311)

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier   +6 more
wiley   +1 more source

Are they half as strong as they used to be? An experiment testing whether age-related social comparisons impair older people's hand grip strength and persistence [PDF]

open access: yes, 2012
OBJECTIVE: To assess how age-related social comparisons, which are likely to arise inadvertently or deliberately during assessments, may affect older people's performance on tests that are used to assess their needs and capability.
Swift, Hannah J.   +2 more
core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

open access: yesAdvanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei   +12 more
wiley   +1 more source

Protocol for a meta-analysis of stereotype threat in African Americans.

open access: yesPLoS ONE
Stereotype threat is a well-known construct in psychology wherein individuals who belong to a negatively stereotyped demographic group underperform on cognitive or academic tasks due to the detrimental effects of a stereotype.
Russell T Warne, Ross A A Larsen
doaj   +1 more source

Stereotype Level of Linguistic Concsiousnes: Socio- and Psycho-Linguistic Grounds

open access: yesОбразование и наука, 2015
The linguistic consciousness is regarded as a multilevel system, its stereotype level being one of the structural bases. Applying a statistic analysis, the author justifies a reflex-driven nature of stereotype statements emphasizing their socio- and ...
L. V. Matevosyan
doaj   +1 more source

Help-seeking helps: help-seeking and group image

open access: yes, 2014
Seeking help from an outgroup can be difficult, especially when the outgroup is known to stereotype the ingroup negatively and the potential recipient cares strongly about its social image.
Greenwood, RM   +5 more
core   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

open access: yesAdvanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia   +4 more
wiley   +1 more source

You Don’t Bend It Like Beckham if You’re Female and Reminded of It: Stereotype Threat Among Female Football Players

open access: yesFrontiers in Psychology, 2019
Originally, the stereotype threat effect – poorer performance due to a fear of fulfilling a negative stereotype about one’s group – was demonstrated for cognitive tasks (e.g. Steele and Aronson, 1995, or Steele, 1997).
Hilmar Grabow, Melanie Kühl
doaj   +1 more source

Double Jeopardy-Analyzing the Combined Effect of Age and Gender Stereotype Threat on Older Workers

open access: yesFrontiers in Psychology, 2021
In this study we aim to analyze the combined effect of age-based and gender stereotype threat on work identity processes (and in particular on authenticity and organizational identification) and on work performance (self-rating performance). The research
Claudia Manzi   +4 more
doaj   +1 more source

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