Results 211 to 220 of about 9,420,423 (308)

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

Advanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu, Fangting Ma, Fan Ding, Luyan Wang, Yunxi Li, Yunzhi He, Xingang Zhang, Siyu He, Dandan Liu   +8 more
wiley   +1 more source

A Planarity-Hindrance Co-Balance Strategy to Develop Antiparallel H-Aggregates With Minimal Absorbance Blueshift for Type I Photodynamic Therapy. [PDF]

Adv Mater
Liu Y, Ji C, Sun Z, Zhu ZH, Tang BZ, Feng G.   +5 more
europepmc   +1 more source

Architecture‐Engineered Semi‐Crystalline Microporous Polymer Membranes for Precise Molecular Separation

Advanced Science, EarlyView.
Guided by a Random Forest model, a π–π‐driven ordered stacking strategy deploys functionally distinct substructures to restrict chain segment motion and increase free volume, while preserving the intermolecular interactions that maintain structural integrity.
Zi‐Meng Xu, Hao Zhuo, Song‐Hui Zhi, Xiao‐Feng Zhong, Pan‐Pan Zhang, Si‐Yuan Yang, Wen‐Yong Yang, Guang‐Yong Shen, Ya‐Zhao Li, Yi Li, Ming Xue   +10 more
wiley   +1 more source

Bypassing Heteronuclear MRI: Metal‐Free Organosilicon Nanotracers for Background‐Free Hotspot 1H Imaging on Clinical Hardware

Advanced Science, EarlyView.
Organosilicon micelles enable background‐free molecular magnetic resonance imaging (MRI) while remaining fully compatible with standard proton (1H) hardware. By exploiting a spectrally silent 1H window at ∼0 ppm, the silicone nanotracer allows hotspot detection by 1H chemical‐shift imaging (CSI) without metals or heteronuclei, enabling direct overlay ...
Martin Orsagh, Dominik Havlicek, Andrea Galisova, Ondrej Sedlacek, Daniel Jirak   +4 more
wiley   +1 more source

Overview of Endomucin in Vascular Homeostasis and Disease. [PDF]

Microcirculation
Yang RF, Wang XR, Wang J, Du HB, Zhao ZA, Zhao ZG.   +5 more
europepmc   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

The Metallophilicity Phenomenon: The Interplay of Steric, Orbital, Dispersion, and Electronic Correlation Effects in Closed-Shell Metal-Metal Contacts. [PDF]

Inorg Chem
Gutiérrez-Sánchez N, Miranda-Rojas S, Mendizabal F.   +2 more
europepmc   +1 more source

Multimodal Bioinspired Self‐Healing Composites Enabling Durable and High‐Efficiency Wearable Perovskite Light‐Emitting Diodes

Advanced Science, EarlyView.
Butterfly wing–inspired intrinsically self‐healing polymer interlayers enable flexible perovskite optoelectronics with high luminance, strain‐insensitive stability, and environmental resilience. These hierarchically structured films redistribute mechanical stress, suppress defect formation, and maintain performance under repeated bending, paving the ...
Loganathan Veeramuthu, Yu‐Chen Wang, Chun‐Tse Tsai, Yen‐Lin Tseng, Xuan Ting King, Tzu‐Ming Hsu, Zhen‐Li Yan, Fang‐Cheng Liang, Pei‐Yin Chen, Georgy Dosovitskiy, Yehonadav Bekenstein, Hyunjin Lee, Tao Zhou, Chi‐Ching Kuo   +13 more
wiley   +1 more source

Cobalt‐Catalyzed Asymmetric Construction of Boron Stereocenters With C–N Axial Chirality

Advanced Science, EarlyView.
A cobalt/Salox‐catalyzed one‐pot annulation enables enantioselective formation of B‐stereogenic centers and C─N axial chirality via C─H/N─H annulation, affording diverse fluorescent products with high stereocontrol and optoelectronic potential. ABSTRACT The efficient construction of boron stereogenic centers alongside axial chirality remains a ...
Subramani Kumaran, Harihara Subramanian Ravi Sankar, Pritam Maity, J. Richard Premkumar, Abir Das, Basker Sundararaju   +5 more
wiley   +1 more source