Results 151 to 160 of about 271,466 (344)

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Steric effects in light-induced solvent proton abstraction. [PDF]

Phys Chem Chem Phys, 2020
Lahiri J, Moemeni M, Magoulas I, Yuwono SH, Kline J, Borhan B, Piecuch P, Jackson JE, Blanchard GJ, Dantus M.   +9 more
europepmc   +1 more source

Steric effects of a homogeneous CuCl₂/solvent system for photocatalytic selective oxidation of benzyl alcohol

, 2022
Chao Meng, Bo Weng
openalex   +2 more sources

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

AI-assisted quantitative deciphering of molecular configuration and steric effects for high-performance zinc battery electrolytes

Communications Materials
Zinc-ion batteries depend on molecular design of electrolyte additives for performance optimization. However, the influence of molecular structure and steric effects on solvation behavior has not been systematically quantified.
Yizhan Gao, Rongkun Sun, Yiqian Shi, Zhigang Shao   +3 more
doaj   +1 more source

Bifunctional Surfaces With Immobilized Antibodies and Bioactive Peptides Mediate Selective Capture and Proliferation of Endothelial Colony‐Forming Cells

Advanced Healthcare Materials, EarlyView.
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level, Marc‐Antoine Campeau, Mohamed A. Elkhodiry, Gaétan Laroche, Jean‐François Tanguay, Corinne A. Hoesli   +5 more
wiley   +1 more source

A Novel Approach to the Evaluation of the Importance of Steric and Electronic Effects in S_NAr Reactions: A Computational, Thermodynamic and ¹H and ¹³C NMR Study of “Meisenheimer‐Type” Adducts in the Benzo[b]thiophene Series

, 2010
Giovanni Consiglio, Barbara Cosimelli, Susanna Guernelli, Camilla Zaira Lanza, Fernando Sancassan, Domenico Spinelli, Marco Stenta   +6 more
openalex   +2 more sources

Steric effects in the diastereoselective reduction of β-ketosulfones [PDF]

, 1988
J. Stuart Grossert, H.R.W. Dharmaratne, T. Stanley Cameron, Beverly R. Vincent   +3 more
openalex   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

RHODIUM(I) COMPLEXES OF BISPHOSPHONITOCARBABORANE(12)S: A COMPUTATIONAL STUDY

Studia Universitatis Babes-Bolyai Chemia, 2016
Density functional calculations indicate that the steric and packing factors seem to play a much more significant role than the electronic effects in influencing the bending of the rhodium(I) complexes of bisphosphonitocarbaborane(12)s.
Menyhárt Botond SÁROSI, Evamarie HEY-HAWKINS   +1 more
doaj