Dual Effect of Steric Hindrance in Non‐Aqueous Amine Absorbents: Navigating the Trade‐Off Between Kinetics and Thermodynamics for Efficient CO2 Capture [PDF]
Advanced ScienceSterically hindered amines (SHAs) offering high theoretical capacity and reduced regeneration energy, yet their molecular mechanism, especially in non‐aqueous solvents, remains unclear.
Xiaoyi Gao +8 more
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Quantifying steric hindrance and topological obstruction to protein structure superposition [PDF]
Algorithms for Molecular Biology, 2021 Background In computational structural biology, structure comparison is fundamental for our understanding of proteins. Structure comparison is, e.g., algorithmically the starting point for computational studies of structural evolution and it guides our ...
Peter Røgen
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Trypsin-functionalized AgAu nanoflowers for enhanced sensing of hydrogen sulfide in diverse foods: dual mechanisms of steric hindrance-mediated biothiols exclusion and silver-driven 30-fold cascade amplification [PDF]
Food Chemistry: XCombining the excellent optical properties, spatial structure specificity and 30-fold cascade signal amplification strategy of the trypsin-stabilized silver‑gold nanoflowers (Try-AgAuNFs), a novel nanosensing system was constructed for improving the ...
Hongyu Chen +7 more
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Steric hindrance-mediated extracellular vesicle size fractionation for rapid prehospital diagnosis of intracerebral hemorrhage [PDF]
Nature CommunicationsDiagnosing intracerebral hemorrhage (ICH) in prehospital settings remains challenging due to unavailability of immediate neuroimaging, clinical overlap with ischemic stroke, and absence of validated circulating biomarkers for time-critical settings ...
Xingjie Wu +14 more
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Increasing Specificity of Targeted DNA Methylation Editing by Non-Enzymatic CRISPR/dCas9-Based Steric Hindrance [PDF]
Biomedicines, 2023 As advances in genome engineering inch the technology towards wider clinical use—slowed by technical and ethical hurdles—a newer offshoot, termed “epigenome engineering”, offers the ability to correct disease-causing changes in the DNA without changing ...
Daniel M. Sapozhnikov, Moshe Szyf
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Unexpected steric hindrance failure in the gas phase F− + (CH3)3CI SN2 reaction [PDF]
Nature Communications, 2022 Base-induced elimination (E2) and bimolecular nucleophilic substitution (SN2) are of significant importance in physical organic chemistry. Here, the authors show that the competing factor of E2 as opposed to steric hindrance determines the low reactivity
Xiaoxiao Lu +6 more
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Investigating the Influence of Steric Hindrance on Selective Anion Transport [PDF]
Molecules, 2019 A series of symmetrical and unsymmetrical alkyl tren based tris-thiourea anion transporters were synthesised and their anion binding and transport properties studied.
Laura A. Jowett +4 more
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Dual-targeting and steric hindrance resolution in HER2 IHC: a novel approach to improve diagnostic sensitivity [PDF]
BMC CancerBackground The HER2 immunohistochemistry (IHC) test is an essential method for detecting breast cancer (BC) and plays a pivotal role in guiding personalized treatment strategies.
Li Luo +8 more
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Pan-H7 influenza human antibody virus neutralization depends on avidity and steric hindrance [PDF]
JCI InsightH7N9 avian influenza virus is a zoonotic influenza virus of public health concern, with a 39% mortality rate in humans. H7N9-specific prevention or treatments for humans have not been approved.
Iuliia M. Gilchuk +9 more
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Substituent effect of Cp2TiCl2 catalyst for ethylene polymerization: A DFT study [PDF]
Polyolefins Journal, 2023 The substituents on cyclopentadienyl (Cp) can regulate the electronic effect and hindrance of the active center in the metallocene catalyst. This modification can greatly change the catalytic activity of the catalyst and affect some features of the ...
Kefeng Xie +5 more
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