Results 1 to 10 of about 1,102 (69)
Investigating the Influence of Steric Hindrance on Selective Anion Transport
Molecules, 2019 A series of symmetrical and unsymmetrical alkyl tren based tris-thiourea anion transporters were synthesised and their anion binding and transport properties studied.
Laura A. Jowett +4 more
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Fluorinated tetrapodal anion transporters
iScience, 2023 Summary: Synthetic anion transporters show potential in treating life-threatening diseases like cystic fibrosis and cancer. However, with increasingly complex transporter architectures designed to control anion binding and transport, it is important to ...
Alexander M. Gilchrist +4 more
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Boosting Anion Transport Activity of Diamidocarbazoles by Electron Withdrawing Substituents
Frontiers in Chemistry, 2021 Artificial chloride transporters have been intensely investigated in view of their potential medicinal applications. Recently, we have established 1,8-diamidocarbazoles as a versatile platform for the development of active chloride carriers.
Krystyna Maslowska-Jarzyna +2 more
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Frontiers in Physiology, 2022 Molecular dynamics (MD) simulations have provided new insights into the organization and dynamics of the red blood cell Band 3 anion exchanger (AE1, SLC4A1).
Antreas C. Kalli +1 more
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Molecules, 2020 Synthetic anion transporters that facilitate chloride transport are promising candidates for channelopathy treatments. However, most anion transporters exhibit an undesired side effect of facilitating proton transport via interacting with fatty acids ...
Alexander M. Gilchrist +6 more
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SLC26A9 as a Potential Modifier and Therapeutic Target in Cystic Fibrosis Lung Disease
Biomolecules, 2022 SLC26A9 belongs to the solute carrier family 26 (SLC26), which comprises membrane proteins involved in ion transport mechanisms. On the basis of different preliminary findings, including the phenotype of SlC26A9-deficient mice and its possible role as a ...
Giulia Gorrieri +2 more
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Scientific Reports, 2021 Ion channel proteins are physiologically important molecules in living organisms. Their molecular functions have been investigated using electrophysiological methods, which enable quantitative, precise and advanced measurements and thus require complex ...
Chihiro Kikuchi +5 more
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A Benzimidazolium-Based Organic Cage with Antimicrobial Activity
Chemistry, 2022 Considering the wide interest in (benz)imidazolium-based drugs, we here report our study on a benzimidazolium-based organic cage as potential antimicrobial and antifungal agent.
Sonia La Cognata +8 more
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Anion Transport Across Human Gallbladder Organoids and Monolayers
Frontiers in Physiology, 2022 Fluid and anion secretion are important functions of the biliary tract. It has been established that cAMP regulates Na+ absorption through NHE3. However, mechanisms of gallbladder anion transport are less defined.
Keyan Zarei +6 more
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Molecules, 2021 Being able to bind, select, and transport species is central to a number of fields, including medicine, materials, and environmental science. In particular, recognizing a specific species from one phase and transporting it across, or into another phase ...
Sozan Najib Abdullah +2 more
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