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Investigating the Influence of Steric Hindrance on Selective Anion Transport [PDF]

open access: yesMolecules, 2019
A series of symmetrical and unsymmetrical alkyl tren based tris-thiourea anion transporters were synthesised and their anion binding and transport properties studied.
Laura A. Jowett   +4 more
doaj   +4 more sources

Tetrapodal Anion Transporters [PDF]

open access: yesMolecules, 2020
Synthetic anion transporters that facilitate chloride transport are promising candidates for channelopathy treatments. However, most anion transporters exhibit an undesired side effect of facilitating proton transport via interacting with fatty acids ...
Alexander M. Gilchrist   +6 more
doaj   +7 more sources

Boosting Anion Transport Activity of Diamidocarbazoles by Electron Withdrawing Substituents [PDF]

open access: yesFrontiers in Chemistry, 2021
Artificial chloride transporters have been intensely investigated in view of their potential medicinal applications. Recently, we have established 1,8-diamidocarbazoles as a versatile platform for the development of active chloride carriers.
Krystyna Maslowska-Jarzyna   +2 more
doaj   +2 more sources

Fluorinated tetrapodal anion transporters

open access: yesiScience, 2023
Summary: Synthetic anion transporters show potential in treating life-threatening diseases like cystic fibrosis and cancer. However, with increasingly complex transporter architectures designed to control anion binding and transport, it is important to ...
Alexander M. Gilchrist   +4 more
doaj   +3 more sources

Anion Transport Across Human Gallbladder Organoids and Monolayers [PDF]

open access: yesFrontiers in Physiology, 2022
Fluid and anion secretion are important functions of the biliary tract. It has been established that cAMP regulates Na+ absorption through NHE3. However, mechanisms of gallbladder anion transport are less defined.
Keyan Zarei   +6 more
doaj   +2 more sources

Anion transport and GABA signaling [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2013
Whereas activation of GABAA receptors by GABA usually results in a hyperpolarizing influx of chloride into the neuron, the reversed chloride driving force in the immature nervous system results in a depolarizing efflux of chloride.
Christian Andreas Huebner   +1 more
doaj   +3 more sources

Anion Transport Using Core Functionalized Hyperbranched Polymers and Evidence of a Dense Packed Limit Based on Molecular Weight [PDF]

open access: yesMolecules, 2021
Being able to bind, select, and transport species is central to a number of fields, including medicine, materials, and environmental science. In particular, recognizing a specific species from one phase and transporting it across, or into another phase ...
Sozan Najib Abdullah   +2 more
doaj   +2 more sources

Transmembrane anion transport promoted by thioamides. [PDF]

open access: yesRSC Adv, 2021
Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-dithioamidocarbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated.
Pomorski R   +3 more
europepmc   +8 more sources

Transmembrane Transport of Bicarbonate by Anion Receptors [PDF]

open access: yesChemPlusChem, 2022
Abstract The development of synthetic anion transporters is motivated by their potential application as treatment for diseases that originate from deficient anion transport by natural proteins. Transport of bicarbonate is important for crucial biological functions such as respiration and digestion.
Luis Martínez-Crespo   +1 more
exaly   +3 more sources

Erythroid anion transport, nitric oxide, and blood pressure [PDF]

open access: yesFrontiers in Physiology
Glycophorin A and glycophorin B are structural membrane glycoproteins bound in the band 3 multiprotein complexes on human red blood cells (RBCs). Band 3 is an erythroid-specific anion exchanger (AE1).
Kate Hsu, Kate Hsu, Kate Hsu
doaj   +2 more sources

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