Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Gold-Catalyzed Addition of β-Ketoesters to Alkenes: Influence of Electronic and Steric Effects in the Reaction Outcome. [PDF]
Molecules, 2018 La-Venia A, Mischne MP, Mata EG.
europepmc +1 more source
Attenuating Nucleophilicity of Titanocene Hydrides Beyond Steric Effects en Route to Fatty Alcohols [PDF]
Andreas Gansäuer +5 more
openalex +1 more source
IL‐2 Free Expansion of T Cells with Immunofilaments
Advanced Healthcare Materials, EarlyView.Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck +4 more
wiley +1 more source
A New Family of Ternary Intermetallic Compounds with Dualistic Atomic Ordering – The ZIP Phases
Advanced Materials, EarlyView.The ZIP phases are ternary intermetallic compounds with dualistic atomic ordering, i.e., they exhibit one face‐centered cubic (fcc; space group Fd3¯$\bar 3$m) variant and one hexagonal (space group P63/mmc) variant. The ZIP phases in the Nb‐Si‐Ni system are the Nb3SiNi2 (fcc) and Ni3SiNb2 (hexagonal) ternary IMCs, crystal structure schematics of which ...
Matheus A. Tunes +24 more
wiley +1 more source
Parameterization of phosphine ligands demonstrates enhancement of nickel catalysis via remote steric effects. [PDF]
Nat Chem, 2017 Wu K, Doyle AG.
europepmc +1 more source
Advanced Materials, Volume 37, Issue 13, April 2, 2025.Leveraging the numerous advantages of ammonium‐ion (NH₄⁺)—including cost‐effectiveness, low corrosiveness, preferential orientation, and rapid diffusion kinetics—aqueous NH₄⁺ batteries (AAIBs) have gained significant attention. This review highlights and evaluates the progress of AAIBs utilizing organic electrode materials such as small molecules ...
Mangmang Shi, Xiaoyan Zhang
wiley +1 more source
The Promise of Solid Lubricants for a Sustainable Future
Advanced Materials, EarlyView.Lubricants are vital for technology, saving energy and resources. The industry seeks sustainable solutions beyond fossil fuels. Solid lubricants offer extremely low friction and reduce environmental impact, especially in harsh conditions. Can these solids truly replace liquid lubricants, or are they limited to extreme applications?
Philipp G. Grützmacher +7 more
wiley +1 more source
Guanine Can Direct Binding Specificity of Ru-dipyridophenazine (dppz) Complexes to DNA through Steric Effects. [PDF]
Chemistry, 2017 Hall JP +10 more
europepmc +1 more source
Steric Effects of Alkyl Substituents on the N–H Stretching Absorptions and Rotational Isomerism of N,N′-Dialkylthioureas [PDF]
, 1977 Yoshiyuki Mido +2 more
openalex +1 more source