Results 41 to 50 of about 254,410 (141)

Digoxin mitigates diethylnitrosamine-induced acute liver injury in mice via limiting production of inflammatory mediators

Saudi Pharmaceutical Journal, 2022
The cardiotonic digoxin has been recently shown to possess an anti-inflammatory potential in numerous metabolic and inflammatory disorders. However, data about digoxin’s impact in the setting of acute liver injury and sterile inflammation are still ...
Mohamed E. Shaker, Mohamed F. Hamed, Ahmed A. Shaaban   +2 more
doaj   +1 more source

Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome

Case Reports in Ophthalmological Medicine, 2017
We report the clinical course of a diabetic patient with bilateral cataract and rubeosis in association with ocular ischemic syndrome and initially treated him with simultaneous intravitreal 2 mg aflibercept and 2 mg triamcinolone acetonide injection at ...
Ceren Durmaz Engin, Ziya Ayhan, Süleyman Men, Aylin Yaman, A. Osman Saatci   +4 more
doaj   +1 more source

Etiological Value of Sterile Inflammation in Preeclampsia: Is It a Non-Infectious Pregnancy Complication?

Frontiers in Cellular and Infection Microbiology, 2021
Understanding of sterile inflammation and its associated biological triggers and diseases is still at the elementary stage. This becomes more warranted in cases where infections are not associated with the pathology.
Sayani Banerjee, Zheping Huang, Zhengke Wang, Akitoshi Nakashima, Shigeru Saito, Surendra Sharma, Shibin Cheng   +6 more
doaj   +1 more source

ORMDL proteins regulate ceramide levels during sterile inflammation

Journal of Lipid Research, 2016
The bioactive sphingolipid metabolite, ceramide, regulates physiological processes important for inflammation and elevated levels of ceramide have been implicated in IL-1-mediated events.
Lin Cai, Clement Oyeniran, Debolina D. Biswas, Jeremy Allegood, Sheldon Milstien, Tomasz Kordula, Michael Maceyka, Sarah Spiegel   +7 more
doaj   +1 more source

Mitochondrial Contribution to Inflammation in Diabetic Kidney Disease

Cells, 2022
Diabetes is the leading cause of chronic kidney disease worldwide. Despite the burden, the factors contributing to the development and progression of diabetic kidney disease (DKD) remain to be fully elucidated.
Alla Mitrofanova, Antonio M. Fontanella, George W. Burke, Sandra Merscher, Alessia Fornoni   +4 more
doaj   +1 more source

Sterile inflammation and pregnancy complications: a review [PDF]

Reproduction, 2016
Inflammation is essential for successful embryo implantation, pregnancy maintenance and delivery. In the last decade, important advances have been made in regard to endogenous, and therefore non-infectious, initiators of inflammation, which can act through the same receptors as pathogens.
Mathieu, Nadeau-Vallée, Dima, Obari, Julia, Palacios, Marie-Ève, Brien, Cyntia, Duval, Sylvain, Chemtob, Sylvie, Girard   +6 more
openaire   +2 more sources

Role of sterile inflammation in fatty liver diseases

Liver Research, 2018
Sterile inflammation is a ubiquitous response of tissues to stress and injury, and occurs to a high degree in the liver. This results in high levels of tissue damage after development of the metabolic syndrome, and with alcohol excess.
Yonglin Chen, Muhammad Nadeem Yousaf, Wajahat Z. Mehal   +2 more
doaj   +1 more source

Sterile inflammation in the liver and pancreas [PDF]

Journal of Gastroenterology and Hepatology, 2013
AbstractgraphicThe ability of tissue injury to result in inflammation is a well‐recognized phenomenon and is central to a number of common liver and pancreatic diseases including alcoholic steatohepatitis and pancreatitis, as well as drug‐induced liver injury, non‐alcoholic steatohepatitis, and pancreatitis from other causes.
Rafaz, Hoque, Ahmad, Farooq, Wajahat Z, Mehal   +2 more
openaire   +2 more sources

Sterile inflammation, cross-presentation, autophagy and adaptive immunity in immunoinflammatory rheumatic diseases

Медицинская иммунология
Proinflammatory extracellular and intracellular DAMPs are the dominant etiological factors of sterile inflammation in immuno-inflammatory rheumatic diseases.
M. Z. Saidov
doaj   +1 more source

Resolution of Sterile Inflammation: Role for Vitamin C

Mediators of Inflammation, 2014
Introduction. Macrophage reprogramming is vital for resolution of acute inflammation. Parenteral vitamin C (VitC) attenuates proinflammatory states in murine and human sepsis.
Bassem M. Mohammed, Bernard J. Fisher, Quoc K. Huynh, Dayanjan S. Wijesinghe, Charles E. Chalfant, Donald F. Brophy, Alpha A. Fowler III, Ramesh Natarajan   +7 more
doaj   +1 more source