Results 31 to 40 of about 262,141 (236)
THE CONTRIBUTION OF INNATE IMMUNE CELLS TO THE PATHOPHYSIOLOGY OF ACUTE STERILE INFLAMMATION- EVIDENCE FROM PRECLINICAL ANIMAL MODELS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut UniversityOne of the most critical factors for managing patients with liver disease is inflammation. The liver mediates numerous functions in the innate immunity, these functions predispose the liver to immunity-mediated liver injury if this inflammation is not ...
Nardeen Eldafashi +3 more
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Frontiers in Pediatrics, 2022 ObjectiveTo assess the association between newborn birth weight and the presence of intra-amniotic infection, presence of sterile intra-amniotic inflammation, and absence of intra-amniotic inflammation in pregnancies with preterm labor with intact ...
Jana Matulova +11 more
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The Sterile Inflammation in the Exacerbation of HBV-Associated Liver Injury
Mediators of Inflammation, 2015 Exacerbation of hepatitis B virus-associated liver injury is characterized by abnormal immune response which not only mobilizes specific antiviral effects but also poses a potentially lethal nonspecific sterile inflammation to the host.
Qiao Yang +4 more
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Sterile Inflammation Fuels Gastric Cancer [PDF]
Immunity, 2018 Constitutively activated NF-κB signaling has long been known to be oncogenic. In this issue of Immunity, O'Reilly et al. (2018) unveil a link between loss of NF-κB1, aberrant STAT1 signaling, sterile inflammation, and the increased expression of immune checkpoint molecules as cancer drivers.
Montinaro, A, Walczak, H
openaire +3 more sources
Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin
Frontiers in Immunology, 2021 Macrophages are highly responsive to the environmental cues and are the primary responders to tissue stress and damage. While much is known about the role of macrophages during inflammatory disease progression; the initial series of events that set up ...
Oindrila Bhattacharjee +11 more
doaj +1 more source
Induction of sterile type 2 inflammation [PDF]
Nature Materials, 2019 Microparticle debris from prosthetic implants has been shown to induce a type 2 inflammatory response through a Bruton’s tyrosine kinase-dependent signalling pathway.
Dimitri A, de Kouchkovsky +2 more
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Multifaceted Roles of CD5L in Infectious and Sterile Inflammation [PDF]
International Journal of Molecular Sciences, 2021 CD5L, a protein expressed and secreted mainly by macrophages, is emerging as a critical immune effector. In addition to its well-defined function as an anti-apoptotic protein, research over the last decade has uncovered additional roles that range from pattern recognition to autophagy, cell polarization, and the regulation of lipid metabolism.
Lidia Sanchez-Moral +5 more
openaire +3 more sources
Sterile Endophthalmitis after Intravitreal Injections
Mediators of Inflammation, 2012 Sterile endophthalmitis appears as an infrequent complication of intravitreal injections and seems to develop mainly in the context of the off-label use of drugs that have not been conceived for intravitreous administration.
Joaquín Marticorena +2 more
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Late stage erythroid precursor production is impaired in mice with chronic inflammation
Haematologica, 2012 Background We and others have shown previously that over-expression of hepcidin antimicrobial peptide, independently of inflammation, induces several features of anemia of inflammation and chronic disease, including hypoferremia, sequestration of iron ...
Olivier D. Prince +14 more
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Cells, 2022 Sterile inflammation either resolves the initial insult or leads to tissue damage. Kidney ischemia/reperfusion injury (IRI) is associated with neutrophilic infiltration, enhanced production of inflammatory mediators, accumulation of necrotic cells and ...
Andrea Ribeiro +8 more
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