Results 31 to 40 of about 202,929 (259)
This contribution focuses on the social treatment of the childbearing duty, the stigma it can produce, as well as the paradoxes of this duty. In every society, women escaping the reproductive injunction are stigmatized in a peculiar way.
Laurence Tain
doaj +1 more source
Tapetum-specific expression of harpinPss causes male sterility in transgenic tobacco
Harpin, an elicitor molecule of bacterial origin induces hypersensitive response (HR) in non-host plants. In an attempt to induce male sterility, harpin was tagged with a signal peptide and expressed downstream to tapetum-specific TA29 promoter resulting
B. Uma +11 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
In the current historiography of the early Swedish welfare state the so-called sterilisation programme, which was established in the 1930s in accordance with the premises of racial hygiene, plays a prominent role.
Christer Nordlund
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Mechanisms of Genic Male Sterility [PDF]
For normal sexual reproductive development, coordination must occur between both male and female organ ontogeny. An abnormality at any point in this process may lead to sterility. Classification of sterility can be divided into heritable and nonheritable
Horner, Harry, Palmer, Reid
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Male Sterility in Cotton [PDF]
Not AvailableMale sterility refers to a condition in which nonfunctional pollen grains are produced in flowering plants. In flowering plants, the first case of male sterility was reported by Koelreuter in 1763.
Suman Bala Singh, Phundan Singh, C D Mayee
core
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source

