Results 31 to 40 of about 202,929 (259)

Le devoir d’enfant à l’ère de la médicalisation : stigmates, retournements et brèches en procréation assistée

open access: yesGenre, Sexualité et Société, 2009
This contribution focuses on the social treatment of the childbearing duty, the stigma it can produce, as well as the paradoxes of this duty. In every society, women escaping the reproductive injunction are stigmatized in a peculiar way.
Laurence Tain
doaj   +1 more source

Tapetum-specific expression of harpinPss causes male sterility in transgenic tobacco

open access: yes, 2012
Harpin, an elicitor molecule of bacterial origin induces hypersensitive response (HR) in non-host plants. In an attempt to induce male sterility, harpin was tagged with a signal peptide and expressed downstream to tapetum-specific TA29 promoter resulting
B. Uma   +11 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hormoner i folkhemmet

open access: yesKulturella Perspektiv, 2008
In the current historiography of the early Swedish welfare state the so-called sterilisation programme, which was established in the 1930s in accordance with the premises of racial hygiene, plays a prominent role.
Christer Nordlund
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Mechanisms of Genic Male Sterility [PDF]

open access: yes, 1995
For normal sexual reproductive development, coordination must occur between both male and female organ ontogeny. An abnormality at any point in this process may lead to sterility. Classification of sterility can be divided into heritable and nonheritable
Horner, Harry, Palmer, Reid
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Male Sterility in Cotton [PDF]

open access: yes, 2002
Not AvailableMale sterility refers to a condition in which nonfunctional pollen grains are produced in flowering plants. In flowering plants, the first case of male sterility was reported by Koelreuter in 1763.
Suman Bala Singh, Phundan Singh, C D Mayee
core  

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

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