Results 41 to 50 of about 188,278 (265)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Male Sterility in Cotton [PDF]
Not AvailableMale sterility refers to a condition in which nonfunctional pollen grains are produced in flowering plants. In flowering plants, the first case of male sterility was reported by Koelreuter in 1763.
Suman Bala Singh, Phundan Singh, C D Mayee
core
© 2017, The Author(s). The sterility test described in pharmacopoeial compendia requires a 14-day incubation period to obtain a valid analytical result.
Dua, K +8 more
core +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Evaluation of the Sterility of PRP Obtained with Multi-bag System (PRPBAG®) [PDF]
Introduction:The aim of this study is demonstrating the sterility of PRPBAG®, a multi-bag completely closed PRP preparation system different than PRP kits in the market and determining preservability of the sterility of PRP produced with PRPBAG® up to 5 ...
Nang Hseng Kyio +6 more
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sub-Lethal Effect of Four Plant Extracts on Growth And Reproductive Parameters of Culex pipines molestus Forskal (Diptera: Culicidae) [PDF]
The ethanol extracts of leaves Alianthus altissima, Carrisa grandiflora, fruits of Citrullus colocynthis and aerial parts of Ruta graveolens was tested against fourth instar larvae of the mosquito, Culex pipines molestua Forskal through sublethal doses ...
Atallah Mekhlif, Mohammad AbdulRazzak
doaj +1 more source
Correlation between the response of maize lines to CMS and their origin
Transferring maize hybrids to a sterile basis is the most important condition for their introduction into production. In this regard, it is important to study the behavior of the initial forms of hybrids, namely self-pollinated lines, in the sterile ...
G. Ya. Krivosheev, A. S. Ignatiev
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source

