Results 71 to 80 of about 351,681 (398)

In vitro Fertilization Procedures with Embryo Transfer and Their Association with Thrombophilia, Thrombosis and Early Antithrombotic Treatments

open access: yesJournal of Blood Medicine, 2020
Pierpaolo Di Micco,1 Vincenzo Russo,2 Daniela Mastroiacovo,3 Marijan Bosevski,4 Corrado Lodigiani5 1Department of Internal Medicine, Fatebenefratelli Hospital of Naples, Naples, Italy; 2Chair of Cardiology, Department of Translational Medical Sciences ...
Di Micco P   +4 more
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Adapting the rice crop to hotter environments: Current and future activities at IRRI [PDF]

open access: yes, 2009
Future climate scenarios are claiming for an increase in global temperature of 2 to 4°C by 2100 in the rice production areas in Asia One of the mandates of the International Rice Research Institute is to predict to what extent the different rice growing ...
Fitzgerald, Melissa A.   +9 more
core  

The Arabidopsis thaliana SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASES1 and 2 control male sporogenesis [PDF]

open access: yes, 2005
The Arabidopsis thaliana SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE (SERK) family of plasma membrane receptors consists of five closely related members. The SERK1 and SERK2 genes show a complex expression pattern throughout development.
Albrecht, Catherine   +4 more
core   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Parthenogenesis as a Solution to Hybrid Sterility: The Mechanistic Basis of Meiotic Distortions in Clonal and Sterile Hybrids

open access: yesGenetics, 2019
Hybrid sterility is a hallmark of speciation, but the underlying molecular mechanisms remain poorly understood. Here, we report that speciation may regularly proceed through a stage at which gene flow is completely interrupted, but hybrid sterility ...
Dmitrij Dedukh   +8 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Method for determination of varietal purity (typicality), hybridity, sterility of seed lots based on the establishment of the quantitative ratio of alleles of DNA markers

open access: yesPlant Varieties Studying and Protection, 2016
Purpose. To develop a conceptually new method for determination of varietal purity (typicality), hybridity, steri­lity of seed lots. Methods of molecular biology (genomic DNA extraction, PCR with SSR markers application, capillary electrophoresis ...
Ж. В. Вдовиченко   +3 more
doaj   +1 more source

Progestational Steroids: Some Moral Problems [PDF]

open access: yes, 1958
EDITOR\u27S NOTE. Physicians now have at their disposal certain new drugs which apparently are proving effective in the correction of various gynecological disorders. But because these drugs can also inhibit ovulation and consequently produce
Lynch, John J.
core   +1 more source

HMS1 Interacts with HMS1I to Regulate Very-long-chain Fatty Acid Biosynthesis and the Humidity-sensitive Genic Male Sterility in Rice (Oryza sativa).

open access: yesNew Phytologist, 2019
Environment-sensitive male sterility (EGMS) lines are widely used in two-line hybrid breeding in rice (Oryza sativa). At present, photoperiod-sensitive genic male sterility (PGMS) lines and thermo-sensitive genic male sterility (TGMS) lines are ...
Huiqiong Chen   +14 more
semanticscholar   +1 more source

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